Natural Product/Pharmacology Postdoctoral Fellow

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Job Description

Natural Product/Pharmacology Postdoctoral Fellow

ID225207

Project Name

UHH-Pharmacy

Posted Date04/03/2025

Closing Date04/10/2025

FTE100.0%

Compensation$4701.00-$4701.00/Month

StateHawaii

IslandHawaii

Job Summary

CLOSING DATE: April 10, 2025, or until filled. Applications received after this deadline may be considered only if the position is not filled or up to the date a selection has been approved by the RCUH (whichever comes first).

Regular, Full-Time, RCUH Non-Civil Service position with the University of Hawaii at Hilo (UHH), The Daniel K. Inouye College of Pharmacy (DKICP), Discovery of novel natural TEAD inhibitors for the chemoprevention of liver tumors, located in Hilo, Hawaii. Continuation of employment is dependent upon program/operational needs, satisfactory work performance, availability of funds, and compliance with applicable Federal/State laws.

MONTHLY SALARY: $4,701/Mon.

DUTIES: Responsible for collecting samples, isolating bacterial/fungal strains (including marine-associated fungi and bacteria, endophytes, soil microbes, arthropod-associated microorganisms, etc.), strain isolation, fermentation, separating/purifying natural products from different natural sources, determining structures using Nuclear Magnetic Resonance (NMR), Mass Spectrometry (MS), Ultraviolet-Visible (UV), and Infrared (IR) spectroscopy; and ordering chemicals, reagents, instruments, and other items used in the lab. Maintains instruments, including Liquid Chromatography Mass Spectrometry (LCMS), High Performance Liquid Chromatography (HPLC), SpeedVac, Lyophilizer, Rota-evaporators, shakers, and incubators. Searches relevant scientific literature, and writes reports detailing the work. Gives literature and research talks at the DKI College of Pharmacy, UHH. Writes manuscripts and grant proposals and presents research data in scientific conferences. Trains laboratory personnel in experimentation techniques. Oversees and provides assistance in training undergraduate and graduate students.

PRIMARY QUALIFICATIONS:

EDUCATION: PhD from an accredited college or university in Chemistry with a specialization in Organic or Natural Product Chemistry, or related field.

EXPERIENCE: Up to one (0-1) year of experience in Microbiology Natural Product Chemistry, Medicinal Chemistry, or Organic Chemistry.

KNOWLEDGE: General knowledge of working in a chemistry research laboratory. General knowledge of chemical and biological waste disposal procedures.

ABILITIES & SKILLS: Ability to collect samples, isolate microorganisms, conduct purification of minor compounds from insufficient crude samples. Ability to work with air- and light-sensitive samples. Ability to run new NMR experiments. Ability to collect Liquid Chromatography/High Resolution Mass Spectrometry (LC/HRMS) data. Ability to maintain an online computer database of samples, compounds, and chemicals present in the laboratory. Ability to interpret 1H- and 13C-NMR, MS, UV, and IR data for structure determination. Ability to follow complex written and oral instructions. Ability to communicate effectively with peers and superiors, both orally and in writing. Ability to use computer-generated spreadsheets to track inventory and use. Post Offer/Employment Condition: Must be able to complete the UH Title IX training within twelve (12) months from date of hire. Must complete the online Hazard Communication training immediately after hire or no later than employee's initial exposure to hazardous chemicals.

PHYSICAL/MEDICAL DEMANDS: Must be able to lift and carry waste containers weighing as much as twenty (20) pounds unassisted.

POLICY/REGULATORY REQUIREMENT: As a condition of employment, employee will be subject to all applicable RCUH policies, procedures, and trainings and, as applicable, subject to University of Hawaii's and/or business entity's policies, procedures, and trainings. Violation of RCUH's, UH's, or business entity's policies and/or procedures or applicable State or Federal laws and/or regulations may lead to disciplinary action (including, but not limited to possible termination of employment, personal fines, civil and/or criminal penalties, etc.).

SECONDARY QUALIFICATIONS:

Experience with modern chromatography and related technologies. Experience with data-mining. Experience with NMR pulse-sequence. Experience with LC/HRMS dereplication of natural products. Experience in microbial collection and culture, and Polymerase Chain Reaction (PCR). Experience with LCMS operation and analysis. Demonstrated experience in chemical modification for configuration determination. Track record of publication in peer-reviewed journals.

INQUIRIES: Dr. Shugeng Cao ... (Hawaii).

APPLICATION REQUIREMENTS: Please go to You must submit the following documents online to be considered for the position: 1) Cover Letter, 2) Resume, 3) Professional References, 4) Copy of Degree(s)/Transcript(s)/Certificate(s). All online applications must be submitted/received by the closing date (11:59 P.M. Hawaii Standard Time/RCUH receipt time) as stated on the job posting. If you do not have access to our system and the closing date is imminent, you may send additional documents to .... If you have questions on the application process and/or need assistance, please call ... or .... Please visit for more information on RCUH's Benefits for eligible employees.

RCUH's mission is to support and enhance research, development and training in Hawaii, with a focus on the University of Hawaii.

RCUH is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, national origin, ancestry, age, disability, genetic information, pregnancy, marital status, reproductive health decision, citizenship, gender identity or expression, domestic or sexual violence victim status, military/veteran status, or other grounds protected under applicable federal and state laws, except as permitted by law.