Scientist 1 - Assay Development/Molecular Biology/ NGS

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This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

Your Role:

At MilliporeSigma, as a Scientist 1 with our R&D Next Generation Sequencing (NGS) group in our Rockville facility, you will function as an integral scientific and technical resource for the implementation of NGS to the field of biosafety testing. Your role is essential for the advancement of the global commercial NGS offerings of the company. You will support the development and implementation of new NGS assays in the field of biosafety testing and genomics and contribute to the advancement of the commercial NGS offerings of the company.

• Function as an integral scientific and technical resource for the implementation of NGS to the field of biosafety testing.
• Support the development and implementation of new NGS assays in the field of biosafety testing and genomics and contribute to the advancement of the commercial NGS offerings of the company.
• Enhance the development of in-house NGS/CRISPR-based assays to increase specificity and lead to adapt in-house NGS/CRISPR- based assays for Gene editing in cell culture.
• Actively collaborate with NGS/CRISPR teams within organization to develop independent gene editing assays.
• Oversee the development, implementation and execution of new commercial NGS assays and support the day-to-day operation of the facility.
• Assist with transfer and validation of new NGS assays onto automated SciClone platform.
• Liaise closely with the NGS laboratory and bioinformatics teams, contribute ideas and recommendations for process improvement and engage in troubleshooting and assay advancement activities.
• Ensure the timely initiation and completion of studies and ensure testing is performed in accordance with SOPs and regulations (cGMP and GLP) for custom/non-routine and new services.
• Analyze complex data, interpret and integrate experimental results with project objectives, and assist technical lead, as applicable.
• Familiarity with NGS data analysis. Liaise closely with in-house bioinformatics teams to analyze NGS data.

Who You Are

Minimum Qualifications:

• Ph.D. in a scientific discipline (i.e., Molecular Biology, Biotechnology, Biochemistry, etc.) with 1+ years working laboratory experience

OR

• Master's degree in a scientific field (i.e., Biology, Biotechnology, Biochemistry, etc.) with 2+ years working laboratory experience

OR

• Bachelor's degree in a scientific field (i.e., Biology, Biotechnology, Biochemistry, etc.) with 5+ years working laboratory experience.

AND

• 1+ years experience NGS library preparations quantifications, and sequencing (Illumina, Nanopore platforms)

Preferred Qualifications:

• Broad working knowledge of NGS field and experience with molecular laboratory practices, techniques, equipment, materials and mathematical calculations.
• Demonstrated experience with major NGS sequencing platforms (Illumina, Nanopore, PacBio, DNABSEQ, Sanger Sequencing).
• Demonstrated NGS DNA/RNA assay development experience, demonstrated ability to develop customized NGS library protocols including usage of Tn5 transposomes.
• Demonstrated experience with PCR/qPCR/ddPCR assay/test development.
• Ability to analyze NGS data on Linux platform; comfortable usage of command line interface.
• Experience in usage of IGV, NCBI, UCSF genome browser, and other NCBI tools.
• Familiarity with industry standard genome sequencing and annotation tools.
• Excellent verbal and written communication skills that have been demonstrated through presentations/seminars, oversight of projects, implementation of new services, etc.
• Ability to work well independently and in a team environment.
• Multi-tasker who can handle multiple high-complexity projects at one time with excellent time management skills and ability to work under minimal supervision.
• Background/experience with CRISPR/Cas assays and/or gene editing.

Pay Range for this position - $84,700 - $131,000

Our ranges are derived from several sources, and largely reliant on relevant industry market data. Should we decide to make an offer, we will consider several factors, including but not limited to your location, skills, experience, career level, and other job-related factors. This role may offer the following benefits: medical, vision, and dental insurance; life insurance; disability insurance; a 401(k) matching program; paid time off; and paid holidays; among other employee benefits. This role may also be eligible for short-term or long-term incentive compensation, including, but not limited to, cash bonuses.

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!