Associate Scientist, Discovery Pharmacology

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.

We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.

This position collaborates with various teams to develop, optimize, and run biological assays, evaluates new technologies, maintains expertise in assay techniques, performs data analysis, and effectively communicates results to support research goals.

Key Accountabilities/Core Job Responsibilities:

• With some guidance, collaborates with project, platform, and pathway teams to develop and optimize biological assays critical to research programs across the organization

• Works closely and collaboratively with different teams to simultaneously support multiple projects when required

• Runs, analyzes, and iteratively makes improvements to core and novel assays with minimal supervision

• With support, evaluates new technologies aimed at expanding DP capabilities

• Establishes expertise on assay techniques and development, including operation of required instrumentation, including but not exclusive to: ELISA, Immunocytochemistry, protein-protein interaction and affinity measurements via SPR, FACS, cell culture

• Performs data analyses and maintains compliance with good record keeping (ELN)

• Supports research teams by contributing data that achieves team goals

• Ability to analyze and synthesize data and communicate results within DP and to research teams being supported by their efforts

Qualifications/Skills:

• MS in Biochemistry, Molecular Biology, Cell Biology, or related field; or a BS in Biochemistry, Molecular Biology, Cell Biology, or related field with 3+ years of industry experience

• Experience with molecular biology and assay techniques including protein detection and interaction measurements (ELISA, MSD, etc), SPR-based or similar molecular affinity measurement, FACS measurement and analysis, immunostaining, cell culture, protein

quantification

• Expertise with standard text, graphic, and presentation software is required, and familiarity with database/data archival software systems is helpful

• Excellent communication, interpersonal and organizational skills

• Desire to work collaboratively across multiple projects

Salary Range: $100,000.00 to $126,667.00 . Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at

This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future.This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future.

Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.