Chemical Biology and Proteomics Research Associate

At Bayer were visionaries, driven to solve the worlds toughest challenges and striving for a world where 'Health for all Hunger for none is no longer a dream, but a real possibility. Were doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our capabilities and redefining impossible. There are so many reasons to join us. If youre hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference, theres only one choice.

Chemical Biology and Proteomics Research Associate

Bayer is a biopharmaceutical company committed to applying our scientific leadership to transform the lives of patients. The Chemical Biology, Imaging & Omics team (CBIO) is growing at the Bayer Research and Innovation Center (BRIC) in Cambridge, MA to contribute to rapidly growing oncology and cardiovascular drug discovery pipelines. In this role you will collaborate with an interdisciplinary team of scientists within the R&D organization to apply innovative methods for target discovery and early-stage drug development. We are seeking an innovative and agile individual with a passion for chemical biology and proteomics in drug discovery and professional development in a peer coaching setting. You will work with colleagues in cross-divisional teams from Pharma in both the US and Europe.

YOUR TASKS AND RESPONSIBILITIES

The primary responsibilities of this role, Chemical Biology and Proteomics Research Associate are to:

• In a lab environment: plan and execute manual or automated MS-based proteomic experiments to progress drug discovery programs, either independently or collaboratively with chemical biologists in the team;
• Perform routine maintenance, QC and troubleshooting of Orbitrap-based mass spectrometers and nano-LC systems;
• Identify opportunities to improve throughput and reproducibility of existing proteomics workflows;
• General laboratory organization (ordering, maintaining lab inventory, protocol & database management);
• Routinely present findings at project team meetings, and collaborate with scientists across R&D functions to effectively answer key scientific questions;
• Stay up to date on emerging methods in the field and maintain a routinely updated electronic lab notebook.

WHO YOU ARE

Bayer seeks an incumbent who possesses the following:

Required Qualifications:

• Bachelor’s Degree in in Proteomics, Biochemistry, Analytical Chemistry, Molecular Biology, or a related field;
• Proficiency in sample preparation techniques for quantitative proteomics, including mammalian cell culture, lysate preparation, protein denaturing, reduction, alkylation, digestion, and peptide clean-up/enrichment protocols;
• Significant hands-on experience with UHPLC-tandem MS systems for proteomics applications, including routine calibrations, quality controls and basic troubleshooting skills;
• Strong communication skills, both written and verbal;
• Strong organizational skills and attention to detail;
• Ability to work collaboratively in a team environment;
• Curious scientific mind with a passion for discovery and problem-solving.

Preferred Qualifications:

• Bachelor’s Degree with 4+ years of experience industrial (pharma/biotech) environment or Master’s degree with 2+ years of experience in an industrial (pharma/biotech) environment;
• Experience in operating Orbitrap or Tribrid-based MS systems and developing related acquisition methods (e.g. DDA, DIA, PRM);
• Experience with liquid handling robots and lab automation tools;
• Familiarity with peptide search engines, data analysis software and bioinformatics tools;
• Knowledge in state-of-the-art proteomics topics, such as target deconvolution (e.g. CETSA, PAL), PTM analysis (e.g. phosphorylation, ubiquitination), covalent inhibitor discovery (e.g. ABPP, intact MS), chemical labeling (e.g. SILAC, TMT), and affinity/proximity-based pulldowns (e.g. AP-MS) is a plus.

Bayer offers a wide variety of competitive compensation and benefits programs. If you meet the requirements of this unique opportunity, and want to impact our mission Science for a better life, we encourage you to apply now. Be part of something bigger. Be you. Be Bayer.
To all recruitment agencies: Bayer does not accept unsolicited third party resumes.

Bayer is an Equal Opportunity Employer/Disabled/Veterans

Bayer is committed to providing access and reasonable accommodations in its application process for individuals with disabilities and encourages applicants with disabilities to request any needed accommodation(s) using the contact information below.