Postdoctoral Fellow University of California Los Angeles

Postdoctoral Fellow
University of California Los Angeles

Requisition Number: JPF10339

Position: Postdoctoral fellow position in functional genomics of neuronal-glial mechanism and drug targets for neurodegenerative dementias. Rexach Lab, UCLA Neurology, Neurogenetics, Human Genetics.

Job Description: Seeking an outstanding applicant with strong research track-record for a competitive post-doctoral fellowship in functional genomics of neurodegenerative disease in the Rexach Lab in the UCLA department of Neurology and Human Genetics. The Rexach group uses integrative multiomics analysis, including single nuclear ATAC and RNA sequencing, to identify glial and immune-related drivers of neurodegenerative dementias, and then studies their function in disease model systems, including human iPSC-derived assembloids and organoids. The goal of this work is to identify and validate new therapeutic targets for neurodegenerative dementias, including Alzheimer's disease and related disorders, none of which have effective cures or treatments. This fellow would lead a functional validation and drug target identification using stem cell-derived models and systems biology to integrate multiomic data generated from models with primary human disease brain data. Salary range is $66737-$80034

Job Duties: Developing, validating and implementing iPSC models of neurodegenerative disease traits and employing them to validate candidate modifiers of disease based on human genetic and functional genetic data.

Skills, Knowledge, and Abilities needed for the position: Experience in cell biology and iPSC modeling of disease is required. Expertise in experimental molecular biology is required, including gene editing and biochemistry. Experience in generating and interpreting data generated by transcriptomics, genomics, proteomics, or related analyses, is preferred. Interest and experience with methods development and innovation is preferred. Experience in basic statistics in required. Experience in advanced statistics for omics research is preferred. Experience in writing first-author scientific manuscripts is required. Strong desire to learn, innovate, discover and collaborate are required. Respect for all colleagues and community is expected and required.

Inquiries: Candidates should send their statement of interest and CV directly to Dr. Rexach for consideration ( ... ).

To apply, please visit:

The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy,

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