Principal Scientist, Early Translational Informatics and Predictive Sciences Neuroscience

Working with Us
Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. Youll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .

We seek a creative and passionate computational scientist with a background in addressing translational questions to join the Early Translational team within Informatics and Predictive Sciences. In this role, you will implement rigorous data analysis practices to lead analyses of high-dimensional readouts from longitudinal patient cohorts. Your analyses will identify biomarkers predictive of patient outcomes and response to therapy. As such, in this highly collaborative role your work will directly inform discovery, biomarker, diagnostic and clinical development.

Responsibilities

Analyze multi-dimensional biomarker data generated from human subjects in clinical trials and other observational cohorts, including RNA-Seq, Exome and Whole Genome Sequencing, high throughput proteomics, and imaging data to validate pharmacodynamics effects, confirm the mechanism of action, and enable patient enrichment strategies.

Conduct analysis independently to integrate and mine large-scale external datasets to further our understanding of neurodegenerative and neuropsychiatric disorders.

Work collaboratively with translational teams to extract insights, generate hypotheses and guide drug development decisions in early clinical development of new therapeutics.

Basic Qualifications:

• Bachelor's Degree 8+ years of academic / industry experience
• Or Master's Degree 6+ years of academic / industry experience
• Or PhD 4+ years of academic / industry experience

Preferred Qualifications:

• Ph.D. in bioinformatics, molecular biology, genetics, engineering, statistics, or similar.
• Four (4) or more years relevant experience in preclinical or clinical research.
• Prior experience in neuroscience research required
• Proficiency using R required and 1+ additional programming language preferred.
• Strong experience in statistical modeling and/or machine learning approaches, such as mixed-effects models, predictive modeling, etc. to represent biological concepts.
• Experience with exploratory biomarker statistical analysis and clinical databases (SDTM/ADaM) is a plus.
• Individual contributor role requiring strong background in -omic (DNA, RNA, epigenetic, proteomic) data analysis and biological interpretation.
• Strong problem-solving and collaboration skills, rigorous and creative thinking
• Ability to communicate effectively with biologists, clinicians and other computational scientists.

The starting compensation for this job is a range from $166,800 - $202,100 plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience .

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Years holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

If you come across a role that intrigues you but doesnt perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as Transforming patients lives through science , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

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