Scientist I /Scientist II, Immunology and Pharmacology

Job Description

The Role:
Title: Scientist I/ Scientist II, Immunology and Pharmacology

Job summary:
The PharmaEssentia Innovation Research Center is building a world-class new drug discovery team in Boston area. We are seeking a highly motivated and independent Scientist I /Scientist II in immunology/cancer pharmacology with a track record of scientific excellence in immunology or oncology, to join our team in Greater Boston, MA USA. As a key project team member, you will be focused on delivering all aspects of in vitro, in vivo, and ex-vivo pharmacology support. You will bring your theoretical and practical expertise to establish assay systems and deliver datasets that will have direct impact on the drug discovery process and pipeline.

The Company:
Its not often that you get the chance to make a real impact on the lives of others, while expanding your own possibilities. Youll find that rare opportunity at PharmaEssentia. Join us, and lets transform lives, together.
PharmaEssentia Corporation is a rapidly growing biopharmaceutical innovator. We are leveraging deep expertise and proven scientific principles to deliver effective new biologics for challenging diseases in the areas of hematology, oncology and immunology, with one approved product and a diversifying pipeline. We believe in the potential to improve both the health and quality of life for patients with limited options today through the combination of rigorous research and innovative thinking.
Founded in 2003 by a team of Taiwanese American executives and renowned scientists from U.S. biotechnology and pharmaceutical companies, today we are listed on the Taipei Exchange (TPEx: 6446) and are expanding our global presence with operations in the U.S., Japan, China and Korea, along with a world-class biologics production facility in Taichung.
Our new research center, PharmaEssentia Innovation Research Center (PIRC), aims to leverage our current expertise in oncology and immunology therapeutic areas to identify and develop novel therapeutic opportunities. Therefore, we are recruiting talented scientists who have deep knowledge in immunology, translational science, bioinformatics and biologics platforms to develop novel drugs through disease-driving biology, novel technology in protein engineering, antibody discovery and new modalities.

PIRC offers a competitive benefit package, including a competitive 401k match, medical/dental/eye care benefits, and other benefits.

Summary of Key Responsibilities:

• Develop, design, conduct and analyze in vitro, in vivo and ex-vivo experiments/data to assess the functions of target molecules.
• Develop in vitro immunological assays to assess the biological functions of target molecules in both human and murine primary immune cells and established cell lines.
• Develop and optimize ex vivo tumor assays, incorporating advanced tumor-on-a-chip technology to closely mimic the tumor microenvironment.
• Support cross-functional teams and work collaboratively with project leaders to ensure the timely generation and dissemination of critical program data.
• Work with Data Science Team to provide evidence for target nomination as well as for clinical development such as novel indication finding and biomarker strategy.
• Establish and maintain a productive Immune-Oncology lab for drug discovery effort with a high standard for the quality of data with optimized experimental protocols and laboratory materials.
• Stay up to date with relevant technical and intellectual scientific expertise in Immune-oncology and Pharmacology and have a genuine passion for this field of research.
• Prepare and deliver clear and accurate scientific presentations for internal and external use.

Essential Qualifications:

• Ph.D. in oncology, immunology, immuno-oncology, pharmacology, pharmaceutical sciences, or a related discipline.
• 1+ years of relevant post-PhD experience in academia or industry.
• Demonstrated scientific capability in area of immunology and oncology research as evidenced by high-quality independent research and high impact peer-reviewed scientific publications, presentations, projects as a leading contributor.
• Comprehensive knowledge of immunology, autoimmunity and cancer immunology.
• Experience in developing complicated FACS-based cell assays, alongside isolation and characterization of primary cells from both mouse and human sources. Experience with a range of in vitro/ex vivo skills, e.g., cell culture, molecular biology, flow cytometry, ELISA, multiplex assay, and proteomics analysis.
• Work independently, assess and report data in a clear and concise manner, with a clear understanding of its implications within the overall context of drug discovery.
• Strong interpersonal and collaboration skills together with evidence of delivery in a team-oriented, collaborative environment.
• Excellent communication and presentation skills: impactful oral and written communication.

Preferred qualification:

• Experience with setting up human tumor ex vivo assays or tumor-on-a-chip technology, including microfluidic platforms and 3D cell culture systems, is highly preferred. Experiences using biologics including peptides and antibodies is preferred but not required.

EEO Statement:
At PharmaEssentia Innovation Research Center (PIRC), we are committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants without regard to race, color, religion, sex, pregnancy (including childbirth and related medical conditions), national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information (including characteristics and testing), military and veteran status, and any other characteristic protected by applicable law. PIRC believes that diversity and inclusion among our team are critical to our success as a global company, and we seek to recruit, develop and retain the most talented people from a diverse candidate pool. PIRC does not accept unsolicited agency resumes. Staffing agencies should not send resumes to our HR team or to any PIRC employees. PIRC is not responsible for any fees related to unsolicited resumes from staffing agencies.

At PharmaEssentia, our goal is to treat as many people with cancer as possible. That means challenging the status quo with better science that leads to better lives. By joining our team, you will not only expand your own possibilities, but you will contribute to expanding options for people with cancer.