Sr. Scientist - FSP - Protein Reagent

  • ThermoFisher Scientific
  • Boston, Massachusetts
  • Full Time

Work Schedule

First Shift (Days)

Environmental Conditions

Adherence to all Good Manufacturing Practices (GMP) Safety Standards

Job Description

At Thermo Fisher Scientific, youll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on now and in the future.

Thermo Fisher's clinical research business is a leading global contract research organization and world leader in serving science. We are passionate, deliberate, and driven by our mission to enable our customers to make the world healthier, safer, and cleaner.

Within our Analytical Services team, we have a functional service provider solution, which is a unique partnership that allows our customers to leverage the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits.

Key responsibilities:

Work as part of a team of scientists that play a critical role in producing recombinant proteins for structural and biochemical/biophysical studies in support of determining target mechanism of action and ligand engagement.

Searching for an individual who is comfortable multi-tasking and working independently on various aspects across recombinant protein platforms.

  • Provide high quality protein reagents for use in downstream applications.
  • Achieve this using different expression systems including bacteria, insect cells, and mammalian cells to produce recombinant proteins for assays and structural biology.
  • Role will be focused on the protein expression and purification.
  • Qualify and characterize your expressed protein using analytical chemistry techniques.
  • There is potential to perform RNA-based and cell-free methodologies.
  • The successful candidate must have strong interpersonal skills, manage, and communicate the production queue and keep rigorous documentation recorded in your ELN. The candidate must be able to work independently, with strong attention to detail, completing assignments within defined time constraints.
Education and Experience:
  • Bachelor's degree in lab sciences such as Chemistry, Biochemistry, Material Science, Immunology, Biology, Molecular Biology or similar
  • Sr. Scientist: Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 4+ years)
  • OR Masters degree and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 2+ years)
  • OR PhD

In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.

Knowledge, Skills and Abilities:
  • Expression of soluble and integral membrane proteins in recombinant systems
  • Transformation, transfection, or transduction of appropriate expression systems
  • Maintenance of mammalian and insect cell lines
  • Protein expression optimization, when needed
  • Protein purification using a variety of techniques including but not limited to affinity, ion exchange and size exclusion chromatography
  • Multi-tasking, experiment design, execution, and analysis
  • Maintain clear records of experimental work and be able to organize, report and communicate their results
Working Environment:

Below is listed the working environment/requirements for this role:

Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.

Able to work upright and stationary and/or standing for typical working hours.

Able to lift and move objects up to 25 pounds

Able to work in non-traditional work environments.

Able to use and learn standard office equipment and technology with

proficiency.

May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.

Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.

Benefits

We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!

Job ID: 479635369
Originally Posted on: 6/3/2025

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