Assoc Scientist Bioscience

Assoc Scientist Bioscience#25-60215

Gaithersburg, MD

All On-site

Job Description

The position resides in the Critical Pipeline Reagent Sciences Group (CPRS) contained within the Purification Process Sciences R D department. Members of the CPRS function work closely with the research scientists and process development scientists to generate pipeline supporting molecules. Position may require weekend work and/or periodic late-nights.

Main duties are as follows:

Generation of biopharmaceutical reagents to advance the R D *** pipeline

Performing purifications for complex biopharmaceutical drugs such as antibodies, bispecific antibodies, fusion proteins, DuetMabs, pDNA, and viruses

Performing conjugations of candidate drugs and anti-IDs to support PK/PD studies

Solving challenging protein purification problems

Performs technology development projects to increase purification efficiency

Coordinating closely with the research department, cell culture group, and analytical biotechnology group in order to meet project timelines and company goals

Analyzing and interpreting analytical and process data

Maintain accurate records of data and actively participate in laboratory organization

Professionally deliver results to internal and external audiences

Supervision: Should be able to function with limited supervision and is expected to work independently on a day-to-day basis. Expectation for independence will increase with time and experience in the position.

Desired Skills:

Highly team-oriented, energetic, critical thinker, organized, capable of multitasking with excellent oral and written skills

Knowledge of

o Basic Protein Chemistry

o Protein Chromatography

o Purification Process Design for Monoclonal Antibodies and Client Proteins

o Basic Analytical Techniques (HPLC and SDS-PAGE Analyses)

o Protein Modification by Conjugation

o Statistics Software and DOE Analysis

Experience performing protein chromatography using Akta/Akta software

Experience performing analytical testing

EEO:

Mindlance is an Equal Opportunity Employer and does not discriminate in employment on the basis of - Minority/Gender/Disability/Religion/LGBTQI/Age/Veterans.