Senior Scientist, Preclinical

Satellite Bio is pioneering the development of a proprietary, groundbreaking technology that can turn cells into an engineered, implantable tissue therapeutic, thereby providing a transformative option for patients with serious disease. Building on 25 years of work in award-winning labs at top academic institutions, the platform is supported by a strong IP portfolio and is backed by a top tier syndicate, led by Polaris Partners, Lightspeed Ventures, aMoon, and Section 32.

We are seeking an experienced, creative, and motivated Senior Scientist to join our team. In this role you will contribute to the company's platform technology of tissue therapeutics. Specifically, you will work in the preclinical team to support in vivo research proof-of-concepts and IND-enabling studies. You will be responsible for designing and characterizing animal models of liver disease, executing relevant studies to characterize drug product engraftment and function in relevant preclinical models, and drafting preclinical study reports in preparation for regulatory submissions. This role will involve effective collaboration across our highly multidisciplinary organization.

This role is a unique opportunity to join an early-stage, well-funded Biotech startup. You will report directly to the Senior Director of Translational Research. This position is full-time with laboratory time being on-site at our facilities located in Newton, MA. Some time may also be required at our vivarium site in Cambridge, MA, depending on study needs.

Responsibilities:

• Develop and characterize animal models of acute and chronic liver diseases
• Design, develop, and execute in vivo experiments utilizing drug products
• Author nonclinical study reports and contribute to regulatory documents (e.g., IND or CTA sections)
• Implement new readouts to characterize drug product function and engraftment in vivo
• Support preclinical activities for regulatory submission
• Direct and manage relationships with external CROs
• Analyze, interpret, and present key results at group and project team meetings to internal and external stakeholders
• Implement and maintain good documentation practices
• Stay current with the literature and technological advances in relevant fields
• Help build a strong internal team with core technical expertise predicated on team member growth and development

Required Qualifications & Experience:

• Ph.D. or D.V.M. with 4+ years of industry experience or M.S. with 8+ years or industry experience
• Training in Cell Biology, Bioengineering, or other life sciences discipline
• Experience working with in vivo teams and designing animal studies
• Hands-on experience with in vivo techniques, including in-life and terminal blood sampling, drug dosing (i.p., i.v., or gavage), small animal surgeries, and tissue collection and processing for downstream assays
• Scientific understanding of cell and molecular biology and how it relates to disease pathology, as evidenced by publications
• Familiarity with the preclinical regulatory requirements for cell therapy programs and/or surgically placed therapeutics/devices is a plus
• Experience leading collaborations with CROs is a plus
• Hands-on experience with relevant assays and techniques, including in vitro cell-based assays, biochemical assays, ELISA and qPCR, is a plus
• Excellent written and verbal communication skills, with the proven ability to build open and collaborative relationships and work effectively as a member of a multidisciplinary team
• Excellent organizational, technical writing, and record keeping skills
• A successful candidate will be an ambitious self-starter, have a strong work ethic, be able to generate high quality work under tight deadlines, and enjoy working in a fast-paced team environment

Please submit your resume (.pdf format) to ...: Provide a summary of the role, what success in the position looks like, and how this role fits into the organization overall.

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