Senior Principal Scientist, Data-Rich Experimentation

Job Description

The Data-Rich Experimentation (DRE) Group within the Process Research & Development (R&D) Enabling Technologies department is seeking highly motivated and technically focused individuals who are looking for opportunities to positively impact our Company's process development practices, while actively supporting drug development in the biologics, vaccine and small molecule spaces.

The DRE group is tasked with identifying, developing, and deploying tools and methodologies aimed at improving the manner in which process understanding is gathered. The technologies we develop are as diverse as the team developing them. Current areas of interest include: high-throughput experimentation and bench-top automation, process modeling and simulation, kinetics and mechanism elucidation, process analytical technologies (PAT), machine learning and data science, etc. Our team is responsible for the invention and application of new tools to support the scientists across Process R&D, and aspires to embed data-intense tools into the fabric of the organizations process development culture.

Additionally, the DRE group is actively driving digital transformation within the Process R&D and Development Sciences and Clinical Supply communities. A key aspect of this role will be the invention, development, and application of cutting-edge digital technologies. Expertise in any of the aforementioned technologies would be considered for this position, however demonstrated skills in process modeling and simulation, machine learning/AI, physical lab automation (including high throughput experimentation and benchtop automation) are particularly desirable.

As a member of the DRE group, the chosen applicant will carry out collaborative research which involves conceiving, designing, planning, and implementing advanced studies aimed at further establishing data-rich experimental methodologies and digital workflows. A high level of innovation, creativity, and initiative along with the ability to plan and execute technically sound experiments are critical, as is a sound understanding of the optimal application of digital technologies. The chosen candidate should also have excellent interpersonal, communication and collaboration skills and exhibit a strength in delivering results on firm deadlines.

Education Minimum Requirements:

• BS, MS, or PhD in Chemistry, Biology, Chemical Engineering, Data Science or a related field.

• Extended academic or industrial experience in a product, process or technology development area:

  • BS +13 years

  • MS +12 years

  • PhD +10 years

Preferred Experience and Skills:

• Effective technical/problem solving skills including grasp of chemistry, biology, chemical engineering and/or data science fundamentals.

• A demonstrated interest in process/technology development, scale-up and deployment.

• A high level of innovation, creativity, and self-initiative along with the ability to plan and organize activities.

Established subject matter expertise in one or more of the following topical areas:

• Vaccines, biologics and/or small-molecule process development

• Process Modeling and Simulation

• High-throughput and Bench-top Automation

• Parallel processing

• PAT

• In Situ Analytics

• Kinetics and Mechanism Elucidation

• Hardware/Software Integration

• Machine Learning/AI

• Data Science

• Data Analytics

• Data Engineering

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one anothers thinking and approach problems collectively.

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U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as remote.

The salary range for this role is

$187,000.00 - $294,400.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employees position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at .

You can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Regular

Relocation:

VISA Sponsorship:

Travel Requirements:

Flexible Work Arrangements:

Not Applicable

Shift:

Valid Driving License:

Hazardous Material(s):

Required Skills:

Biological Sciences, Biological Sciences, Biopharmaceutics, Business, Cell Line Development, Cell Line Engineering, Clinical Judgment, Collaborative Communications, Collaborative Research, Communication, Data Science, Digital Technology, Digital Transformation, Drug Development, Human Health Risk Assessment, Immunochemistry, Immunology, Innovative Thinking, Interpersonal Relationships, Mechatronics, Mentorship, Molecular Biology, Omics Technologies, Process Characterization, Process Simulation {+ 3 more}

Preferred Skills:

Job Posting End Date:

06/28/2025

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