Scientist II- Protein Expression
- Astrix Technology
- South San Francisco, California
- Full Time
Scientist II- Protein Expression**
Laboratory
south san francisco, CA, US
Pay Rate Low: 48.00 | Pay Rate High: 52.00
+ Added - 23/06/2025
Apply for Job
_Our esteemed client, a trailblazing global pharmaceutical powerhouse, renowned for their expertise in developing and manufacturing a wide array of world-class pharmaceutical drugs, life-saving vaccines, and innovative animal-health products, is in search of a skilled_ **_Scientist II- Protein Expression_** _to join their dynamic team in South San Francisco, CA!_
**Job type:** 1 year contract
**Pay rate:** $48/ hr. -$52/ hr.
**Location:** South San Francisco, CA
**Job Description:**
We are seeking a skilled Scientist II- Protein Expression, to support recombinant protein production and characterization efforts for early discovery research. This role involves hands-on work in mammalian cell culture, transfection, small-scale expression, and protein purification using both traditional and high-throughput methods.
**Responsibilities:**
+ Maintain and propagate CHO cells in suspension culture
+ Perform transient and stable transfections (CHO, HEK293)
+ Express and purify proteins (e.g., monoclonal and bispecific antibodies, Fc-fusions) using bench-top and magnetic-bead methods
+ Execute fed-batch cultures in shake flasks, tube spins, and multi-well plates
+ Perform analytical QC: SDS-PAGE, HPLC/UPLC, UV-Vis, NanoDrop, CESDS
+ Track data and maintain documentation using ELNs and analytical tools
+ Support multiple projects in a fast-paced, collaborative lab environment
**Qualifications:**
+ B.S. in Biochemistry, Cell/Molecular Biology, Bioprocess Engineering, or related field + 3 years experience (or M.S. + 1 year)
+ Proficient in mammalian cell culture, aseptic technique, and protein expression
+ Basic experience in protein purification and analytical characterization
+ Strong organizational skills, attention to detail, and ability to multitask
+ Familiar with Vicell, metabolite analyzers, ELN, MS Office; experience with Dotmatics, Benchling, or Spotfire is a plus
_*This job description is a complete list of all desired skills, but not all are required. We strongly encourage candidates who have some of the skills to apply. We look forward to a conversation to learn more about you! *_
\#INDBH
\#LI-DNP
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.
Laboratory
south san francisco, CA, US
Pay Rate Low: 48.00 | Pay Rate High: 52.00
+ Added - 23/06/2025
Apply for Job
_Our esteemed client, a trailblazing global pharmaceutical powerhouse, renowned for their expertise in developing and manufacturing a wide array of world-class pharmaceutical drugs, life-saving vaccines, and innovative animal-health products, is in search of a skilled_ **_Scientist II- Protein Expression_** _to join their dynamic team in South San Francisco, CA!_
**Job type:** 1 year contract
**Pay rate:** $48/ hr. -$52/ hr.
**Location:** South San Francisco, CA
**Job Description:**
We are seeking a skilled Scientist II- Protein Expression, to support recombinant protein production and characterization efforts for early discovery research. This role involves hands-on work in mammalian cell culture, transfection, small-scale expression, and protein purification using both traditional and high-throughput methods.
**Responsibilities:**
+ Maintain and propagate CHO cells in suspension culture
+ Perform transient and stable transfections (CHO, HEK293)
+ Express and purify proteins (e.g., monoclonal and bispecific antibodies, Fc-fusions) using bench-top and magnetic-bead methods
+ Execute fed-batch cultures in shake flasks, tube spins, and multi-well plates
+ Perform analytical QC: SDS-PAGE, HPLC/UPLC, UV-Vis, NanoDrop, CESDS
+ Track data and maintain documentation using ELNs and analytical tools
+ Support multiple projects in a fast-paced, collaborative lab environment
**Qualifications:**
+ B.S. in Biochemistry, Cell/Molecular Biology, Bioprocess Engineering, or related field + 3 years experience (or M.S. + 1 year)
+ Proficient in mammalian cell culture, aseptic technique, and protein expression
+ Basic experience in protein purification and analytical characterization
+ Strong organizational skills, attention to detail, and ability to multitask
+ Familiar with Vicell, metabolite analyzers, ELN, MS Office; experience with Dotmatics, Benchling, or Spotfire is a plus
_*This job description is a complete list of all desired skills, but not all are required. We strongly encourage candidates who have some of the skills to apply. We look forward to a conversation to learn more about you! *_
\#INDBH
\#LI-DNP
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.
Job ID: 482540423
Originally Posted on: 6/24/2025
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