Postdoctoral Scientist - Renal Biology

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. Were looking for people who are determined to make life better for people around the world.

The Diabetes, Obesity and Complications Therapeutic Area (DOCTA) of Eli Lilly and Company, focuses on the discovery of biologic, small molecule and genetic therapeutics for the treatment of diabetes, obesity and associated complications.

We are seeking a highly motivated and experienced scientist as a postdoctoral researcher to join our Indianapolis Diabetes, Obesity and Complications research team. This position will be focused on developing and implementing novel cellular models and renal organoid systems for the purpose of advancing our understanding of renal biology and to enable interrogation of novel disease pathways and therapeutic targets. The successful candidate will have a strong background in in vitro pharmacology, stem cell biology, tissue engineering, and organoid technology. This position offers an exciting opportunity to contribute to innovative research aimed at understanding kidney development and disease. The ideal candidate is an innovative, independent, and dynamic lab-based research scientist preferably with expertise in preclinical cardiorenal in vitro model development and characterization.

Key Responsibilities:

• Design and conduct experiments to generate and characterize renal organoids from human pluripotent stem cells.
• Develop and test protocols for organoid culture, differentiation, and functional assays to understand renal biology and investigate pathways of interest.
• Develop and characterize novel, complex cellular in vitro disease models to interrogate disease biology and assess therapeutics of novel drug targets.
• Collaborate with interdisciplinary teams to integrate organoid models with other renal experimental systems.
• Analyze and interpret data, prepare manuscripts for publication, and present findings at scientific conferences.

Qualifications:

• Ph.D. in a relevant field such as stem cell biology, developmental biology, or tissue engineering

Preferred Experience:

• Extensive experience with stem cell culture, organoid culture and characterization, in renal systems preferred, but not required.
• Proficiency in molecular biology techniques, imaging, and data analysis.
• Strong publication record in peer-reviewed journals.
• Excellent communication and teamwork skills.
• Experience with CRISPR/Cas9 gene editing and single-cell RNA sequencing.
• Knowledge of kidney physiology and pathology.

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Actual compensation will depend on a candidates education, experience, skills, and geographic location. The anticipated wage for this position is

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lillys compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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