Senior Scientist, Protein Characterization, Mass Spectrometry

• Job title Senior Scientist, Protein Characterization, Mass Spectrometry
• Function Discovery & Pre-Clinical/Clinical Development
• Sub function Biotherapeutics R&D
• Category Senior Scientist, Biotherapeutics R&D (ST6)
• Location Malvern / United States of America
• Date posted Jun 27 2025
• Requisition number ...W
• Work pattern Fully Onsite

This job posting is anticipated to close on Jul 28 2025. We may however extend this time period, in which case the posting will remain available on www.careers.jnj.com to accept additional applications.

Description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biotherapeutics R&D

Job Category:

Scientific/Technology

All Job Posting Locations:

Malvern, Pennsylvania, United States of America

Job Description:

About Innovative Medicine:

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at

We are searching for the best talent for a Senior Scientist, Protein Characterization, Mass Spectrometry to be in Malvern, PA

Purpose:

The Therapeutics Discovery & Supply-Analytical Development (TDS-AD) is recruiting for a Senior Scientist located in Malvern, PA. We discover and develop creative large molecule solutions to address significant unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases.

The Analytical Development organization is continuing to build key scientific expertise in protein and vaccine characterization, and primary structure elucidation! We need a hardworking scientist willing to bring their expertise to exciting efforts in novel areas of protein characterization.

You will join the Primary Structure team within the Characterization group in the TDS-AD department to conduct product characterization and process development activities.

You will be responsible for:

• Operating state-of-the-art LC and MS instrumentation
• Learning and applying different software packages for LCMS/protein analysis
• Performing LCMS-based quantitation of post-translational modifications
• Designing and implement peptide mapping / MS experiments on monoclonal antibodies and recombinant proteins to assess sequence coverage and sites of modification
• Participating in IND, IMPD, BLA, and other regulatory filings
• Developing test methods, provide documentation and write scientific reports.
• Conducting testing to support analytical development, manufacturing process development, process validations, and manufacturing investigations
• Leading or facilitating technical discussions and participate in cross-functional teams at project-related meetings

Qualifications / Requirements:

Education:

• A Ph.D. in chemistry, biochemistry or a related field is required

Required:

• Hands-on experience with LC-MS is required

Preferred:

• Proficiency at running and trouble-shooting assays is preferred
• Experience maintaining high quality documentation, analyzing and accurately interpreting data, and preparing reports, and SOPs is preferred
• Strong written and verbal communication and excellent interpersonal skills is preferred
• An understanding and experience in the application of various GXP concepts is preferred

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (...) or contact AskGS to be directed to your accommodation resource.