Principal Scientist - Safety Pharmacology

Principal Scientist - Safety Pharmacology Join Amgen as a Principal Scientist - Safety Pharmacology and contribute to our mission of serving patients. Since 1980, Amgen has been a pioneer in biotech, focusing on Oncology, Inflammation, General Medicine, and Rare Diseases, impacting millions of lives annually. Our culture is collaborative, innovative, and science-driven. We seek passionate professionals eager to tackle challenges and make a difference in patients' lives while advancing their careers. Role Overview The Principal Scientist will join the Translational Safety and Bioanalytical Sciences (TS&BA) team in Thousand Oaks, CA, supporting drug development from target identification through clinical phases. This role involves designing and executing in vitro assays, collaborating across teams, and innovating in safety strategies, especially related to ion channel and cardiac function. Responsibilities Serve as an electrophysiologist supporting investigative activities using electrophysiology techniques. Develop translational safety strategies addressing challenges in the drug pipeline. Apply expertise in ion channel biophysics and pharmacology, particularly cardiac-related, to assay development and validation. Utilize techniques such as patch clamp, MEA, or calcium imaging, and possibly incorporate AI or machine learning. Communicate findings effectively and collaborate within a multidisciplinary team. Qualifications Basic: PhD, PharmD, or MD in a relevant field with 2+ years electrophysiology experience; or Masters with 5+ years; or Bachelors with 7+ years. Preferred: Industry experience in electrophysiology. Benefits & Compensation Competitive salary, comprehensive benefits, bonus and incentive plans, stock options, time-off, flexible work arrangements, and career development opportunities. Application Details Applications are accepted until the position is filled. Amgen is an equal opportunity employer committed to diversity and inclusion. Reasonable accommodations are available for applicants with disabilities. Additional Information Position level: Mid-Senior; Employment type: Full-time; Industry: Biotechnology/Research. Web Reference AJF/857148664-430 Posted Date Sat, 14 Jun 2025 To apply for this position you will complete an application form on another website provided by or on behalf of BioSpace . Please note JobShark - California Jobs is not responsible for the application process on any external website.