- We are seeking a highly motivated and collaborative Associate Scientist to join our Dermatology Immunology group within Discovery Research.
- This individual will support early- through late-stage discovery programs by supporting complex in vitro experiments to study skin inflammation and immune biology.
- The ideal candidate has hands-on experience in primary cell culture, functional immunoassays, and an interest in complex 3D models like spheroids, organoids, or organ-on-chip systems.
- Onsite Expectations: Role is primarily lab-based. ~90% onsite for experimental execution, ~10% for data analysis and study design.
- In Vitro Model Development: Support and execute in vitro assays using primary skin and immune cells to model inflammatory disease mechanisms.
- Assay Execution: Perform proliferation, differentiation, and co-culture experiments. Support immunoassays such as ELISA, MSD, and luminescent readouts.
- Complex Systems: Work with or support 3D skin models, organoids, or microfluidic-based organ-on-chip systems. Experience is a plus but not required.
- Data & Documentation: Analyze and interpret experimental results. Document work clearly in electronic lab notebooks and present findings to the team.
- Techniques: Utilize cell culture, pipetting, qPCR, immunoassays, and support flow cytometry or imaging-based analysis where appropriate.
- Protocol Development: Adapt existing SOPs and contribute to optimization of assay workflows.
- Cross-functional Collaboration: Partner with scientists across dermatology, immunology, and other functional teams to support program goals.
- Bachelors degree with 3+ years of relevant lab experience, or Masters degree with 0 years experience - Associate Scientist I
- Bachelors degree with 5+ years of experience, or Masters degree with 2+ years of experience - Associate Scientist II
- Extensive experience with primary cell cultures and in vitro cell based assays is required.
- Experience with Immunoassays like ELISAs, MSDs is required
- Experience in complex in vitro models (i.e. spheroids, organoids, organ-on-a-chip, microfluidics) is preferred
- Experience in Flow Cytometry and Imaging is preferred but not required
- Able to work both independently and as part of a team when required
- Experience working with skin-relevant cell types (keratinocytes, fibroblasts, endothelial and immune cells).
- Familiarity with 3D or microfluidic systems (e.g., spheroids, organoids, organ-on-chip).
- Experience with immunoassays such as ELISA, MSD, or luminescence platforms.
- Exposure to flow cytometry, imaging, is preferred but not required.
- Strong data organization, communication, and teamwork skills.
- dermatology
- immunology
- skin cells
- keratinocytes
- fibroblasts
- endothelial cells
- immune cells
- primary cell culture
- invitro assays
- cell based assays
- ELISA
- MSD
- immunoassays
- 2D/3D cell culture
- co-culture
- invitro models
- spheriods
- organoids
- microfluidics
Job ID: 483959931
Originally Posted on: 7/3/2025
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