Sr. Computational Chemist**
Kelly Science & Clinical is seeking a **Sr.** **Computational Chemist** for a **6-month contract** position at a cutting-edge client in **San Diego, CA.** If youre passionate about bringing the latest scientific discoveries to life and are ready to take the next step in your career, trust The Experts at Hiring Experts.
**Pay:** $50-70/hour
**Schedule:** Mon-Fri Day. 3-4 days onsite
**Overview**
This client is an industry-leading company thats leading the way in neuroscience-focused drug discovery and development. The Client is expanding its R&D chemistry capabilities and is seeking a skilled Computational Chemist to join their growing team. In this role, you will apply computational methodologies to design optimized compounds with balanced properties across drug discovery programs, from early lead identification to late-stage optimization. You will work closely with medicinal chemists, DMPK scientists, structural biologists, and pharmacologists to drive impactful compound design.
**Responsibilities:**
+ Apply structure-based design and molecular modeling techniques to support drug discovery
+ Contribute to the development of in-silico modeling platforms within the chemistry department
+ Generate productive hypotheses using protein-ligand docking and SAR analysis
+ Develop and maintain machine learning/AI models for DMPK and in-vitro biology endpoints
+ Facilitate compound design using predictive computational technologies
+ Collaborate with cross-functional teams to interpret experimental results and guide compound optimization
+ Identify and implement new computational methods to enhance the Clients drug discovery platform
+ Participate in multidisciplinary teams to improve lead optimization and identify development candidates
+ Stay current with scientific literature and integrate innovations into the computational platform
+ Engage stakeholders across research functions to deliver and exchange key results
**Qualifications:**
+ BS in Chemistry with 5+ years of relevant experience in computational chemistry, cheminformatics, or protein-ligand modeling
+ OR MS/MA in Chemistry with 3+ years of similar experience
+ OR 3+ years of post-Ph.D. experience in a related field
+ Strong knowledge of structure-based design, molecular modeling software (e.g., Schrodinger, CCG, OpenEye)
+ Experience with machine learning/AI predictive modeling and cheminformatics tools
+ Excellent problem-solving, analytical, and communication skills
+ Ability to work independently and collaboratively in a fast-paced, multidisciplinary environment
**What happens next:**
Once you apply, youll proceed to next steps if your skills and experience look like a good fit. But dont worry even if this position doesnt work out, youre still in our network. That means our team of expert Science & Clinical recruiters will have access to your profile, making your opportunities limitless.
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As part of our promise to talent, Kelly supports those who work with us through a variety of benefits, perks, and work-related resources. Kelly offers eligible employees voluntary benefit plans including medical, dental, vision, telemedicine, term life, whole life, accident insurance, critical illness, a legal plan, and short-term disability. As a Kelly employee, you will have access to a retirement savings plan, service bonus and holiday pay plans (earn up to eight paid holidays per benefit year), and a transit spending account. In addition, employees are entitled to earn paid sick leave under the applicable state or local plan. Click here ( for more information on benefits and perks that may be available to you as a member of the Kelly Talent Community.
Why Kelly Science & Clinical?
Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire industry experts just like you. Our team creates expert talent solutions to solve the worlds most critical challenges. Every day, we match science professionals with dream jobs that fit their skills, interests, and career goalsits the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background and education in science, so we know a thing or two about the science market and how to get your expertise noticed.
About Kelly
Work changes everything. And at Kelly, were obsessed with where it can take you. To us, its about more than simply accepting your next job opportunity. Its the fuel that powers every next step of your life. Its the ripple effect that changes and improves everything for your family, your community, and the world. Which is why, here at Kelly, we are dedicated to providing you with limitless opportunities to enrich your lifejust ask the 300,000 people we employ each year.
Kelly is committed to providing equal employment opportunities to all qualified employees and applicants regardless of race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or any other legally protected status, and we take affirmative action to recruit, employ, and advance qualified individuals with disabilities and protected veterans in the workforce. Requests for accommodation related to our application process can be directed to the Kelly Human Resource Knowledge Center. Kelly complies with the requirements of Californias state and local Fair Chance laws. A conviction does not automatically bar individuals from employment. Kelly participates in E-Verify and will provide the federal government with your Form I-9 information to confirm that you are authorized to work in the U.S.
Kelly Services is proud to be an Equal Employment Opportunity and Affirmative Action employer. We welcome, value, and embrace diversity at all levels and are committed to building a team that is inclusive of a variety of backgrounds, communities, perspectives, and abilities. At Kelly, we believe that the more inclusive we are, the better services we can provide. Requests for accommodation related to our application process can be directed to Kellys Human Resource Knowledge Center. Kelly complies with the requirements of Californias state and local Fair Chance laws. A conviction does not automatically bar individuals from employment.
Kelly Science & Clinical is seeking a **Sr.** **Computational Chemist** for a **6-month contract** position at a cutting-edge client in **San Diego, CA.** If youre passionate about bringing the latest scientific discoveries to life and are ready to take the next step in your career, trust The Experts at Hiring Experts.
**Pay:** $50-70/hour
**Schedule:** Mon-Fri Day. 3-4 days onsite
**Overview**
This client is an industry-leading company thats leading the way in neuroscience-focused drug discovery and development. The Client is expanding its R&D chemistry capabilities and is seeking a skilled Computational Chemist to join their growing team. In this role, you will apply computational methodologies to design optimized compounds with balanced properties across drug discovery programs, from early lead identification to late-stage optimization. You will work closely with medicinal chemists, DMPK scientists, structural biologists, and pharmacologists to drive impactful compound design.
**Responsibilities:**
+ Apply structure-based design and molecular modeling techniques to support drug discovery
+ Contribute to the development of in-silico modeling platforms within the chemistry department
+ Generate productive hypotheses using protein-ligand docking and SAR analysis
+ Develop and maintain machine learning/AI models for DMPK and in-vitro biology endpoints
+ Facilitate compound design using predictive computational technologies
+ Collaborate with cross-functional teams to interpret experimental results and guide compound optimization
+ Identify and implement new computational methods to enhance the Clients drug discovery platform
+ Participate in multidisciplinary teams to improve lead optimization and identify development candidates
+ Stay current with scientific literature and integrate innovations into the computational platform
+ Engage stakeholders across research functions to deliver and exchange key results
**Qualifications:**
+ BS in Chemistry with 5+ years of relevant experience in computational chemistry, cheminformatics, or protein-ligand modeling
+ OR MS/MA in Chemistry with 3+ years of similar experience
+ OR 3+ years of post-Ph.D. experience in a related field
+ Strong knowledge of structure-based design, molecular modeling software (e.g., Schrodinger, CCG, OpenEye)
+ Experience with machine learning/AI predictive modeling and cheminformatics tools
+ Excellent problem-solving, analytical, and communication skills
+ Ability to work independently and collaboratively in a fast-paced, multidisciplinary environment
**What happens next:**
Once you apply, youll proceed to next steps if your skills and experience look like a good fit. But dont worry even if this position doesnt work out, youre still in our network. That means our team of expert Science & Clinical recruiters will have access to your profile, making your opportunities limitless.
p#1
As part of our promise to talent, Kelly supports those who work with us through a variety of benefits, perks, and work-related resources. Kelly offers eligible employees voluntary benefit plans including medical, dental, vision, telemedicine, term life, whole life, accident insurance, critical illness, a legal plan, and short-term disability. As a Kelly employee, you will have access to a retirement savings plan, service bonus and holiday pay plans (earn up to eight paid holidays per benefit year), and a transit spending account. In addition, employees are entitled to earn paid sick leave under the applicable state or local plan. Click here ( for more information on benefits and perks that may be available to you as a member of the Kelly Talent Community.
Why Kelly Science & Clinical?
Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire industry experts just like you. Our team creates expert talent solutions to solve the worlds most critical challenges. Every day, we match science professionals with dream jobs that fit their skills, interests, and career goalsits the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background and education in science, so we know a thing or two about the science market and how to get your expertise noticed.
About Kelly
Work changes everything. And at Kelly, were obsessed with where it can take you. To us, its about more than simply accepting your next job opportunity. Its the fuel that powers every next step of your life. Its the ripple effect that changes and improves everything for your family, your community, and the world. Which is why, here at Kelly, we are dedicated to providing you with limitless opportunities to enrich your lifejust ask the 300,000 people we employ each year.
Kelly is committed to providing equal employment opportunities to all qualified employees and applicants regardless of race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or any other legally protected status, and we take affirmative action to recruit, employ, and advance qualified individuals with disabilities and protected veterans in the workforce. Requests for accommodation related to our application process can be directed to the Kelly Human Resource Knowledge Center. Kelly complies with the requirements of Californias state and local Fair Chance laws. A conviction does not automatically bar individuals from employment. Kelly participates in E-Verify and will provide the federal government with your Form I-9 information to confirm that you are authorized to work in the U.S.
Kelly Services is proud to be an Equal Employment Opportunity and Affirmative Action employer. We welcome, value, and embrace diversity at all levels and are committed to building a team that is inclusive of a variety of backgrounds, communities, perspectives, and abilities. At Kelly, we believe that the more inclusive we are, the better services we can provide. Requests for accommodation related to our application process can be directed to Kellys Human Resource Knowledge Center. Kelly complies with the requirements of Californias state and local Fair Chance laws. A conviction does not automatically bar individuals from employment.
Job ID: 483993516
Originally Posted on: 7/3/2025
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