USA-Research Associate II (Scientific)

USA-Research Associate II (Scientific)#25-63622

Waltham, MA

All On-site

Job Description

Title: Research Associate/ Sr. Research Associate Contractor, Capsid Engineering- NGS

Location: Waltham, MA

Type of position: Full Time

Position Overview:

***'s Genomic Medicine Unit based in Waltham, MA is looking for a highly motivated candidate focused on next generation sequencing for the development of Client technological strategies in capsid discovery. The successful candidate will play a pivotal role in the Genomic Medicine Unit in identifying improved AAV capsids through sequencing of plasmids/ viruses/ animal tissues to enable gene therapy programs from early discovery research through development, in a variety of disease areas. This is a 1-year contract role, with possibility of extension.

Key Tasks & Responsibilities:

Support and lead the implementation of next-generation sequencing techniques to characterize plasmid/ AAV libraries.

Collaborate cross-functionally with team members to process RNA samples for RNA-seq of in vitro and in vivo screening studies.

Implementation of multiple state-of-the-art techniques in molecular biology and biochemistry.

Initiate, design, analyze, and present experiments at internal meetings.

Maintain accurate records of experiments and analyses.

Maintain effective communication with manager and other colleagues.

Qualifications:

A Bachelor's or Master's degree in biotechnology or allied fields with at least two years of direct next-generation sequencing experience.

Prior experience with the following is preferred:

o Amplicon sequencing of DNA libraries

o RNA-seq with cells and/ or tissues

o Operation of Illumina Seq instruments

o Familiarity with NGS data analysis platforms

o Experience with laboratory automation for sequencing

Excellent organizational skills to manage and prioritize schedules, quality control steps, and data analysis.

Excellent speaking, reading, and writing skills.

Curiosity and a willingness to work in a highly collaborative team environment.

Candidates must be authorized to work in the USA.

About GMU:

***'s integrated, cross-disciplinary Genomic Medicine Unit (GMU) is accelerating progress toward gene and cell therapies by combining an array of technologies, ranging from, viral (AAV) and non-viral (Lipid Nano Particles, LNP) gene-delivery platforms. GMU's mission is to develop and manufacture transformative genetic therapies for patients with rare and common diseases, using viral and non-viral nucleic acid delivery system. Our vision is to establish cutting edge platform technologies of gene editing, silencing, and augmentation, along with manufacturing platforms to enable broad access to genomic therapies for unmet need.

GMU's AAV Technologies Laboratory is working on bringing safer gene therapies for the patients by identifying Client AAV capsids for gene therapies with augmented tropism and immunological profiles. We rely on in depth understanding of AAV biology, high throughput assays, and sophisticated quantitative models.

*** Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

*** is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions.

With more than 100,000 people in 100 countries, *** is transforming scientific innovation into healthcare solutions around the globe.

***, Empowering Life

At *** diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.

EEO:

Mindlance is an Equal Opportunity Employer and does not discriminate in employment on the basis of - Minority/Gender/Disability/Religion/LGBTQI/Age/Veterans.