Bioprocessing Chemist I

Company Description

ABOUT LGC CLINICAL DIAGNOSTICS:

LGC Clinical Diagnostics develops and manufactures a comprehensive portfolio of catalogue and custom-developed diagnostic quality solutions and component materials for the extended life sciences industry. We partner with IVD assay developers, pharmaceutical, CRO and academic institutions in commercialization activities across the entire diagnostic pipeline. Laboratorians and diagnostic professionals across disciplines of clinical chemistry, immunochemistry, serology, molecular diagnostics, and clinical genomics rely on LGC's products to support accurate and reliable diagnostic results.

Our operating entities include Maine Standards Company, SeraCare Life Sciences, and Technopath Clinical Diagnostics, which are in vitro diagnostics (IVD) manufacturers of quality measurement tools (calibrators, controls, linearity, EQA/PT, biological materials), the Native Antigen Company, which is a manufacturer and supplier of viral antigens and LGC Proficiency Testing a global leader in PT schemes. We operate FDA-registered and ISO 13485-accredited facilities in Maine (USA), Massachusetts (USA), Maryland (USA), Tipperary (Ireland), ISO 9001-accredited facility in Oxford, UK, and Traverse City, Michigan US.

Each day, our world-class staff, scientific expertise, operational efficiency, and superior quality systems are ready to support the range of advanced technologies that collectively improve patient outcomes - from the widely adopted and established through to cutting-edge NGS and precision diagnostics.

Job Description

Job Purpose

The Bioprocessing Chemist I role at LGC offers an outstanding chance to join a dedicated team, aiding in the efficient production and upkeep of our biomaterial supply. You will work together on manufacturing tasks as per a set schedule. Tasks involve managing inventory and creating solutions, buffers, and necessary materials for bioprocessing. Adhering to Good Manufacturing/Laboratory Practices (GMP or GLP), keeping organized records, and guaranteeing product quality are key.

Reporting to the Bioprocessing Supervisor, you will coordinate with other departments, such as Production Planning. Your role will involve analysis and using scientific discretion within pre-established guidelines to make independent decisions about moderate to complex adjustments and calculations. You will employ general to moderately advanced laboratory equipment and techniques to perform tasks of varying complexity under both direct and indirect supervision. Routine analysis and interpretation of test results against established acceptance criteria will be key, as will using your judgement to determine appropriate courses of action.

Key Responsibilities

• Maintain accurate records of work performed according to GLP, cGMP, and QSR requirements.
• Conduct protein purification using various methods, including column chromatography, following established procedures.
• Apply tangential flow filtration for protein separation.
• Prepare production and pilot reagents, buffers, and other solutions as per written procedures and protocols.
• Operate basic and advanced laboratory equipment, such as HPLC and AKTA systems, proficiently.
• Assist R&D with scale-up, process optimization, process validations, and technology transfers for new product introductions.
• Lead projects of moderate complexity aimed at process and product improvements.
• Perform routine maintenance of laboratory equipment.
• Test incoming raw materials.

Qualifications

Minimum Qualifications:

• Minimum 2 years of direct experience in a laboratory setting.
• Bachelor's degree or equivalent experience in a life science or physical science field closely related to protein chemistry.
• Basic knowledge of different protein separation, purification, and characterization techniques.
• Ability to work independently and interact effectively across the organization.

Preferred Qualifications

• 2+ years of experience in a regulated environment (i.e. USDA/FDA/ISO13485).
• Experience and ability to implement automated column separation systems and workflows.

Physical Demands

The physical demands are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

• May require prolonged sitting and working at a computer monitor. Repetitive motion using a keyboard or certain laboratory equipment for long periods. Occasionally required to lift and move material weighing up to 30 lbs.

Work Environment The work environment characteristics are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

• Agreeable work environment typical of an open office setting with some exposure to noise from office machines.
• Most work is performed with biological or chemical hazardous materials in a laboratory environment.

Additional Information

ABOUT LGC:

LGC is a leading, global life science tools company, providing mission-critical components and solutions into high-growth application areas across the human healthcare and applied market segments. Its high-quality product portfolio is comprised of mission-critical tools for genomic analysis and for quality assurance applications, which are typically embedded and recurring within our customers' products and workflows and are valued for their performance, quality, and range.

OUR VALUES

• PASSION
• CURIOSITY
• INTEGRITY
• BRILLIANCE
• RESPECT

EQUAL OPPORTUNITIES

LGC strongly believes that every job applicant and employee should be valued for their individual talents regardless of age, disability, race, color, ethnic or national origin, sex, sexual orientation, gender reassignment, marital or civil partnership, pregnancy or maternity, religion, or belief. Short listing, interviewing and selection will always be carried out without regard to gender, sexual orientation, marital status, color, race, nationality, ethnic or national origins, religion or belief, age, or trade union membership.

For more information about LGC, please visit our website www.lgcgroup.com

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