Senior Associate Scientist--Systems Biology

POSITION SUMMARY

At Pfizer we deliver breakthrough medicines that change patients lives. Our Discovery Technologies team plays a vital role in this mission through enabling the discovery and development of biologics therapeutics. In La Jolla, we are dedicated towards redirecting the immune cells against cancer through the application of bispecific and multispecific antibodies.

Based at our La Jolla site, your research will uncover Pfizers next biologic oncology therapeutics. Your responsibilities include design and development of cell-based assays, liquid samples handling and automation, and high throughput screening (HTS) of biologic drug candidate molecules.

You will work closely with colleagues in Bio Medicine Design and Tumor Biology groups to innovate and develop the next-generation of immune cell engagers.

POSITION RESPONSIBILITIES

• Maintain and manage mammalian cell cultures.

• Develop cell assays through cell line engineering.

• Enable therapeutic antibody discovery through in vitro cell-based assays and high throughput screen.

• Operate liquid handling and automation.

• Analyze, organize, and present data in small and large group meetings.

• Conduct relevant scientific literature search to aid in experimental design.

BASIC QUALIFICATIONS

• B.S. degree and 3+ years experience in general cell biology and cell-based assays OR

• MS degree and 1+ years experience in general cell biology and cell-based assays

• Experience with mammalian cell culture.

• Experience with lentiviral protein expression system.

• Experience with cell-based assays including but not limited to luciferase reporters, ELISA, MSD, NanoBRET, cell viability.

• Experience independently designing, planning, executing, and interpreting experiments.

PREFERRED QUALIFICATIONS

• Experience with plasmid design, cloning, lentivirus, and generation of stable cell lines

• Experience with flow cytometry

• Experience with live cell imaging with Incucytes

• Experience with SnapGene or similar molecular biology design software

• Familiarity with drug discovery, automation, and HTS.

Work Location Assignment: On Premise

The annual base salary for this position ranges from $66,500.00 to $110,900.00. In addition, this position is eligible for participation in Pfizers Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of lifes moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care providers name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

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