Research Lab Tech I / Trauma Immunology

Site: The Brigham and Women's Hospital, Inc.

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Job Summary

This position is for a Research Lab Tech I with dual roles. The first role is to conduct basic cellular immunology research using mass cytometry (CyTOF) to characterize and phenotype human and mouse immune cell subsets. The second role is to assist running the CyTOF Antibody Resource and Core that serves the Harvard Medical Area community. These two roles will be accomplished simultaneous with the technician splitting their time equally between both roles.

The Research Lab Tech will work on studies to profile human blood immune cells from patients with a variety of pathologies, including but not limited to autoimmunity, cancer, and traumatic injury. Mouse disease model studies will also be used to study immune cell responses to injury, infections, and radiation. The technician will work in tandem with another technician on day-to-day operations of the CyTOF antibody resource.

Qualifications

The technicians daily activities will involve validating and testing CyTOF antibody panels, cell preparation, cell staining with CyTOF antibodies, and data analysis. The technician will also help order supplies, prepare specialized reagents, and assist others in the lab or collaborators with CyTOF technology, animal research work, and other associated experimental techniques.

PRINCIPAL DUTIES AND RESPONSIBILITIES:

Help run the CyTOF Antibody Resource and Core conjugating antibodies, validating conjugations, fulfilling orders, troubleshooting user requests, and participate in scientific collaborations with Core users (leading to publications) Process human and mouse tissue into cell suspensions for experiments and to validate CyTOF-ready antibodies Consult and interact with CyTOF users on the technical features of the technology Analyze CyTOF staining data using software for multidimensional cell staining data Train others in the laboratory on using CyTOF technology and other techniques Work as a team on specific studies to profile human and mouse blood cells or tissue cells to identify disease-specific phenotypes.

QUALIFICATIONS:

BS or BA required, concentration in biology, microbiology, chemistry, or related biological sciences.

0-2 years of practical experience in the field

SKILLS/ ABILITIES/ COMPETENCIES REQUIRED: (MUST be realistic, neither overstated nor understated, and related to the essential functions of the job.)

1. Basic laboratory skills

2. Computational skills and knowledge of how to use R programming or similar platform

3. Organizational skills and ability to focus on details

4. Good interpersonal and communication skills

5. Ability to demonstrate professionalism

Additional Job Details (if applicable)

Remote Type

Onsite

Work Location

45 Francis Street

Scheduled Weekly Hours

40

Employee Type

Regular

Work Shift

Day (United States of America)

EEO Statement:

The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veterans Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at .... Mass General Brigham Competency Framework

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