Scientist I, Cancer Immunology

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

As a key player in our Cancer Immunology team, you will:

• Develop, design, conduct and analyze in vitro, in vivo and ex-vivo experiments to characterize novel RAS pathway and other oncogenic pathway-targeted therapies and inform patient selection for monotherapy and combination therapy strategies.

• Develop in vitro immunological assays to assess the biological functions of candidate drug targets and therapeutic mechanisms in both human and murine primary immune cells and established cell lines.

• Support cross-functional teams to generate novel insights that fuel drug development and ensure the timely dissemination of critical program data.

• Stay up to date with relevant technical expertise and latest discoveries in tumor immunology

• Prepare and deliver clear and accurate scientific presentations for internal meetings and external conferences.

Required Skills, Experience and Education:

• Ph.D. degree in immunology, cancer biology or a related discipline with demonstrable track record of excellence in tumor immunology and/or immunotherapy.

• Hands-on experience in 'state of the art' immunology techniques including multi-parameter flow cytometric analyses, cytokine analysis, functional assays with immune cells, cell biology and molecular biology.

• Comprehensive knowledge of oncogenic signaling pathways, role and function of immune cells in cancer, as well as immunotherapies

• Self-motivated, independent, rigorous, well-organized experimentalist with a desire to continue in a laboratory-focused role.

• Excellent written and verbal communication skills.

• Strong track record of research productivity as evidenced by high-quality, impactful publications.

• Strong interpersonal and collaboration skills together with evidence of delivery in a team-oriented, collaborative environment.

Preferred Skills:

• Understanding of cancer plasticity and drug tolerance/persistence/resistance is desirable

• Hands-on experience with mouse models to evaluate the efficacy and mechanisms of action of therapeutic agents; experience with humanized mouse models is desirable

The base salary range for this full-time position is $115,000 to $144,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

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