Research Associate (Seattle, WA) 100% onsite

Research Associate

Duration: 12+ months

Interview: MS TEAMS

100% Onsite!, Seattle, WA

Work Schedule- M-F; Standard Business Hours!

Job Description

The primary focus of this Associate Scientist will be to support process development, production, and characterization of early and late-stage viral vectors (lentiviral vectors and/or adeno-associated viruses). This position will be providing technical subject matter expertise with internal and/or external development and manufacturing collaborators for activities including tech transfer, process characterization, and pre-clinical or clinical process lifecycle management.

Responsibilities:

• Design, execute, and troubleshoot upstream development experiments supporting next-generation LVV production
• Identify, onboard, and develop novel upstream technologies in collaboration with internal and external partners
• Provide experimental design and executional support to team members
• Support cross-functional development efforts e.g. downstream process development, high-throughput process development
• Generate representative crude harvest material to support downstream development activities
• Work independently and within teams to design, execute, and analyze experiments
• Maintain accurate and detailed laboratory notebook and documentation
• Summarize and present data in group meetings and contribute to group discussions and team strategy
• Author technical reports and study memos

Basic Qualifications:

• B.S. with 2+ years of experience or M.S. with 0-2 years of hands-on upstream experience
• Experience with suspension culture of mammalian cells in shake flasks and small stirred tank bioreactors
• Experience with transient transfection operations to produce viral vectors (e.g. adeno-, retro-, lenti)
• Hands-on process development experience
• Independently motivated with ability to mulit-task, problem-solve, and coordinate activities within a team
• Ability to design experiments with design of experiment (DOE) approaches, perform experiments, and interpret the results using statistical software (ex. JMP)

Preferred Qualifications:

• Degree in biological or chemical engineering, biochemistry, or bio-related field
• Experience in the development of viral vectors (e.g. adeno-, retro-, lenti-), including successful transfer for GMP manufacturing
• Experience with single-use technologies.