Associate Scientist, Analytical Development (Mass Spectrometry)

Job Title:

Associate Scientist, Analytical Development (Mass Spectrometry)

Location:

San Diego, CA

Position type:

FLSA:

Full time

Exempt

Department:

Finance ID:

Technical Development and Operations

7625-Q224-18

Profoundly Improve Peoples lives by Revolutionizing the Delivery of RNA Therapeutics

At Avidity Biosciences, we are passionate about the impact of every employee in realizing our vision of improving peoples lives by delivering a new class of RNA therapeutics. Avidity is revolutionizing the field of RNA with its proprietary AOCs, which are designed to combine the specificity of monoclonal antibodies with the precision of oligonucleotide therapies to address targets and diseases previously unreachable with existing RNA therapies. If you are a committed, solution-oriented thinker, join us in making a difference and become part of our growing culture that is integrated, collaborative, agile and focused on the needs of patients.

Avidity Biosciences, Inc.'s mission is to profoundly improve people's lives by delivering a new class of RNA therapeutics - Antibody Oligonucleotide Conjugates (AOCs). Utilizing its proprietary AOC platform, Avidity demonstrated the first-ever successful targeted delivery of RNA into muscle and is leading the field with clinical development programs for three rare muscle diseases: myotonic dystrophy type 1 (DM1), Duchenne muscular dystrophy (DMD) and facioscapulohumeral muscular dystrophy (FSHD). Avidity is broadening the reach of AOCs with its advancing and expanding pipeline, including programs in cardiology and immunology through internal discovery efforts and key partnerships. Avidity is headquartered in San Diego, CA. For more information about our AOC platform, clinical development pipeline, and people, please visit www.aviditybiosciences.com and engage with us on LinkedIn and X .

The Opportunity

We are seeking an Associate Scientist to join the Analytical Development group who is experienced and committed to developing and running mass spectrometry methods to support our AOC research and clinical programs. This is a hands-on position with responsibilities that require daily lab work, data analysis, and interpretation of data that will be shared with cross-functional teams and key stakeholders. The position will report to the Associate Director, Analytical Development and be a part of Avidity's growing CMC/Technical Operations team.

What You Will Contribute

• Design and perform experiments, analyze experimental data, report results, and provide feedback on appropriate next steps such as assay optimization or follow-up experiments.
• Develops and qualifies analytical methods to support AOC release, stability, and extended characterization testing
• Implements novel analytical techniques to overcome analytical challenges in the characterization of AOCs.
• Documents experiments in electronic notebooks and writes technical reports summarizing findings.
• Provide updates and present data proactively and regularly in group and CMC meetings.
• Ensures adherence to applicable regulations, including FDA, EMA, ICH, GMP, and internal Avidity policies.
• Contributes to the company's core values (agile, visionary, integrated, and diverse)
• Perform other duties as required.

What We Seek

• MS in chemistry, biology, or pharmaceutical sciences; or BS with at least 4 years of experience with mass spectrometry analysis of biologics.
• Knowledge of antibody and/or oligonucleotide analytical separation and mass spectrometry techniques.
• Prior experience with various laboratory techniques including LC-MS/MS, HPLC, and CE.
• Proven ability to thrive and enable success in a cross-functional and collaborative environment.
• Excellent communication and interpersonal skills and the ability to facilitate constructive, expedient problem-solving.
• Ability to multi-task, manage conflict, and work in a fast-paced environment.

What We Will Provide To You

• The base salary range for this role is $87,000 - $113,000. The final compensation will be commensurate with such factors as relevant experience, skillset, internal equity and market factors.
• Avidity offers competitive compensation and benefits, which include the opportunity for annual and spot bonuses, stock options, and RSUs, as well as a 401(k) with an employer match. In addition, the comprehensive wellness program includes coverage for medical, dental, vision, and LTD, and four weeks of time off.
• A commitment to learning and development which includes a variety of programming internally developed by and for Avidity employees, opportunities for job-specific training offered by industry, and an education reimbursement program.