- The Biotherapeutics and Genetic Medicine Group is seeking a highly motivated scientist for initiating the lentiviral delivery platform for gene therapy in a newly established Genetic Medicine team.
- The candidate will work collaboratively with cross-functional and therapeutic area teams to advance companys lentiviral gene therapy pipeline.
- The ideal candidate will have strong expertise and experience in lentivirus vector engineering, production, analytics and in vitro screening, as well as experience in managing CROs for lentiviral production.
- Collaborate with cross-functional and therapeutic area teams to advance novel lentiviral vectors into pipeline
- Design and engineer lentiviral vectors and manage lentiviral production by leveraging internal and CRO resources.
- Help build and establish analytical and cell-based screening assays (e.g., p24, VCN, SupT1 titration, ELISA, qPCR, ddPCR, WES, FACS, and endotoxin assay)
- Maintain a comprehensive Electronic Lab Notebook documenting experiments
- Maintain a high level of productivity in the team with clear daily, detailed, and accurate documentation of experiments
- Author technical reports and protocols
- Understand and enforce company culture, teamwork, safety, appropriate handling of materials in an BSL2 environment
- Perform all activities in compliance with applicable regulations, policies and guidelines
- Bring a "can do" spirit to work and deliver on other responsibilities as assigned
- Ph.D. in biology or a relevant field with 5+ years of experience in lentiviral vector-based gene therapy in addition to post-doctoral experience; or MS with at least 10 years of relevant experience; industrial experience highly desired
- Strong expertise and experience in lentiviral vector design, engineering and production
- Experience in managing CROs for lentiviral production
- Experience in analytical and screening methods for characterization of lentiviral vector products
- Experience in CAR-T cell therapy
- Experience in in vivo lentiviral targeted delivery is a plus
- Ability to work effectively in a highly collaborative and dynamic environment
- Excellent verbal and written communication skills
- Excellent organization and collaborative skills
- Detail oriented with a passion to deliver quality results
- lentiviral vector-based gene therapy
- LVV
- Lentivirus
- ELISA
- QPCR
- DDPCR
- FACS
Job ID: 486875423
Originally Posted on: 7/25/2025
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