R&D Scientist

About Us

Sino Biological is an internationally recognized reagent supplier and contract research organization, listed on ChiNext of the Shenzhen stock exchange (301047 Sino Biological Inc.). Sino Biological's core technology platform is its in-house developed mammalian cell-based recombinant expression system, which employs proprietary reagents and processes for the efficient production of antigens and antibodies. With its main manufacturing facilities in Beijing, China, Sino Biological also has a growing global presence with a US headquarters in the greater Philadelphia area, a bioprocessing facility in Houston, Texas, and subsidiaries in Frankfurt, Germany, and Tokyo, Japan. As part of its major global expansion, the company has established the Center for Bioprocessing (C4B) in Houston, Texas, located in the renowned Texas Medical Center at Levit Green. C4B is equipped with state-of-the-art facilities and staffed by a team of experts, driving innovation in bioprocessing. Job Title: R&D Scientist

Location: Houston, TX

Department: Center for Bioprocessing (C4B), Sino Biological US, Inc.

Position Type: Full-time Job Description

This position is suited for experienced scientists with a strong background in protein purification, characterization, and bioprocess development in an industrial environment. The Scientist or Senior Scientist will play a key role in leading and executing downstream process development, including chromatography-based purification and recombinant protein quality assessment. The role involves independent design and optimization of purification workflows, supervision of junior staff, and collaboration with upstream and operations teams to support internal pipeline and client-based programs. Responsibilities include method development, hands-on operation of FPLC systems (e.g., Cytiva AKTA), and analytical techniques such as HPLC-SEC, ELISA, and DSF to evaluate product quality and process consistency. The successful candidate will demonstrate strong scientific judgment, attention to detail, and the ability to document and communicate results clearly in a fast-paced, team-oriented setting. Flexibility is required, including potential weekend work and early or late weekday shifts based on project demands. Responsibilities

• Lead bioprocessing projects and supervise associates in wet lab activities related to recombinant protein and antibody production.
• Design and improve upstream and downstream bioprocessing workflows, contribute to project planning, and review project information to provide feedback on recombinant protein and antibody design for upstream and downstream processes.
• Develop and optimize assays to evaluate protein interactions, stability, and quality controls, including BLI, ELISA, HPLC-SEC, DSF, and related analytical methods.
• Oversee maintenance, calibration, and troubleshooting of bioprocessing instruments.
• Collaborate with cross-functional teams to ensure alignment with project goals.
• Maintain accurate and organized documentation, including experimental records and technical reports.
• Ensure compliance with laboratory safety practices and OSHA guidelines. Requirements
• MS or PhD in Biochemistry, Biotechnology, Molecular Biology, or a related field.
• Several years of relevant experience in recombinant protein and antibody design, expression, purification, and characterization, as well as novel bioprocess development.
• Proficiency in protein characterization assays such as BLI, ELISA, and DSF, and analytical techniques such as HPLC-SEC.
• Strong knowledge of mammalian expression systems and downstream purification workflows, including HEK293/CHO expression and Cytiva AKTA or other FPLC platform applications.
• Industrial experience is preferred.
• Excellent organizational, analytical, and communication skills.
• Willingness to work a flexible schedule, including occasional morning, evening, and weekend hours.
• Must be able to lift and move 25-50 lbs as needed. Why Join Us?
• Competitive compensation package.
• Learn directly from industry professionals in a global biotech company.
• Career growth opportunities and mentorship.
• A welcoming, team-first workplace that celebrates diversity and collaboration. Note:

Only shortlisted candidates will be contacted for interviews. If selected, an HR team member will reach out to schedule a quick phone interview using the contact information provided in your resume. Sino Biological Inc. is an equal-opportunity employer. We celebrate diversity and are committed to building an inclusive environment for all employees. #LI-Onsite