Senior Scientist, Discovery & Translational Research

Work closely with Alnylam's Target Discovery, Human Genetics, Multi-Omics, Platform, and Clinical Research teams Acquire deep knowledge of target biology to serve as a Research Lead for specific target(s) Design and execute proof-of-concept experiments in animal and in vitro disease models to support targets at various stages of development Design studies, coordinate activities, and lead from the bench Oversee lead discovery activities for the selection of drug candidates for further development Develop assays to monitor target engagement/pharmacodynamic responses Work with multifunctional teams to shepherd a drug candidate through the lead selection and development process to the clinic Initiate and manage relationships with contract research organizations (CROs) and/or academic collaborators, including the development of research plans and data analysis Mentor junior scientists Collaborate and communicate results with key stakeholders throughout the organization PhD + postdoc in Cell Biology, Molecular Biology, Biochemistry, Immunology, Genetics, or a related field At least 3+ years of industry experience, or equivalent, are preferred. Expertise in skeletal muscle (e.g., rare muscle diseases) or cardiovascular basic research or translational medicine (e.g., heart physiology, heart failure, arrhythmias) Existing focus on disease biology and prior experience with mammalian disease models are preferred Strong publication record Solid organizational skills and the ability to multitask are a must The successful candidate will have strong interpersonal and communication skills, a track record of working on teams, an interest in learning new biology, and a passion for lab work