Senior Scientist (Branford, CT)

We're hiring a Senior or Principal Scientist to join our Biotherapeutics team's collaborative group focused on designing and advancing first-in-class immune-engaging biologics. If youre a protein engineer who thrives in the lab and wants your work to move swiftly toward patients, this role offers real opportunity, purpose, and scientific challenge.

What Youll Work On

• Design and optimize novel antibody and bispecific formats that power our next-generation immunotherapies
• Lead antibody engineering from idea to construct to bench including expression, purification, and characterization
• Improve key attributes like affinity, stability, specificity, and PK using modern tools and data
• Drive developability assessments with platforms like SPR, BLI, DSC, DLS, ciEF, and LC-MS
• Collaborate across functional teams to support candidate selection and preclinical development
• Develop and refine functional assays for biologic characterization
• Present findings in a clear, compelling way to multidisciplinary teams
• Mentor junior scientists (if interested) and help shape our growing discovery organization

What You Bring

• PhD in Biochemistry or a related field and 5+ years of industry experience (or)
• MS with 10+ years in antibody engineering roles
• Strong foundation in antibody structurefunction relationships and biologics drug development
• Expertise in protein design, expression, purification, and biophysical characterization
• Deep experience with bispecific or multispecific formats and familiarity with T cell engagers
• Working knowledge of structureactivity relationships and/or molecular modeling is a plus
• Experience with mammalian expression systems (e.g., CHO/HEK), cell-based assays, or phage/yeast display is valuable
• Strong communication, data interpretation, and cross-functional collaboration skills

Why Youll Love Working Here

• Direct impact: Your ideas and experiments will influence platform design and help shape clinical programs
• Cutting-edge science: Work on a truly novel immunotherapy approach in a scientifically rigorous, fast-moving environment
• Personal growth: Take on visible, high-impact projects in a startup culture where contributions are recognized and development is supported
• Collaborative culture: Join a tight-knit, mission-driven team that values open communication, learning, and teamwork
• Mission with meaning: Be part of a company working to give more patients real hope in the fight against cancer