Research Associate III-Investigative Toxicology

Software Guidance & Assistance, Inc., (SGA), is searching for a Research Associate III- Investigative Toxicology f or a CONTRACT assignment with one of our premier Pharmaceutical Services clients in South San Francisco, CA .

Responsibilities :
Firm has an open Research Associate III position in the Investigative Toxicology group within the department of Translational Safety located in our South San Francisco campus. The Investigative Toxicology group's goal is to use ex vivo and in vitro tools to assess safety liabilities and mechanisms of toxicities observed pre-clinically to support the entire portfolio spanning discovery through development. This laboratory-based role involves performing, qualifying, and implementing biological assays and technologies to support the Investigative Toxicology group. This is an ideal position for a researcher who is enthusiastic about learning and contributing to projects with a broad range of techniques. As such the position requires excellent communication and collaboration skills, a desire to learn about and integrate multiple aspects of drug toxicity, and a passion for lab-based research. This position is in the Investigative Toxicology Group within the department of Translational Safety in Firm's Research and Early Development organization.

• Investigative Toxicology group is to elucidate the mechanisms underlying toxicities that are observed non-clinically and/or in clinical trials through hypothesis driven research.
• Collaborate with scientists across the organization to support the overall safety assessment for our novel therapeutics spanning drug discovery through clinical development and marketing.
• Provide fit-for-purpose wet lab-based investigation to address target safety assessment, lead optimization, and issue mitigation by employing state-of-the-science in vitro and ex vivo approaches.
• Establish new platforms and technologies to support a constantly changing portfolio, novel modalities, and emerging therapeutic area needs.
• Maintaining documentation related to protocol execution and results.
• Write protocols and contributing to final reports as appropriate.

• Perform experiments involving immortalized and primary cell culture, cell viability assessment, Luminex/ELISAs, gene expression analysis, high content screening, confocal microscopy, and flow cytometry.
• Adhere to departmental SOPs to ensure study integrity and quality.
• Conducting experiments with a high level of independence and initiative.
• Perform tasks with minimal direct supervision for routine methods and studies commonly employed by the team.
• Role will Involve:
  • Sitting or standing for extended periods.
  • Performing repetitive tasks such as cell culture, pipetting, and labeling tubes.
  • Collaboration across the Investigative Toxicology team and with key stakeholders.
  • Work with potentially hazardous materials including (but not limited to): chemotherapeutics, biological hazards, and human primary cells.

Required Skills :

• Bachelors (BS/BA) in pharmacology, pharmaceutical science, biology, bioengineering, chemistry, physiology, or related discipline is required
• 1-3+ years of laboratory experience with hypothesis-driven research.
• Ability to analyze, integrate, and present data in a presentation is required.
• Experience with immortalized and/or primary cell culture, cell viability assessment, Luminex/ELISAs, gene expression analysis, high content screening, confocal microscopy, and flow cytometry is highly desired.
• Experience in cell culture

Preferred Skills :

• Masters (MS) degree is desirable, but not required
• Experience with these methodologies is desirable
• Experience with complex in-vitro model systems is highly desired.

SGA is a technology and resource solutions provider driven to stand out. We are a women-owned business. Our mission: to solve big IT problems with a more personal, boutique approach. Each year, we match consultants like you to more than 1,000 engagements. When we say let's work better together, we mean it. You'll join a diverse team built on these core values: customer service, employee development, and quality and integrity in everything we do. Be yourself, love what you do and find your passion at work. Please find us at .

SGA is an Equal Opportunity Employer and does not discriminate on the basis of Race, Color, Sex, Sexual Orientation, Gender Identity, Religion, National Origin, Disability, Veteran Status, Age, Marital Status, Pregnancy, Genetic Information, or Other Legally Protected Status. We are committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, and our services, programs, and activities. Please visit our company to request an accommodation or assistance regarding our policy.
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