Senior Scientist, Bioconjugates

• Job title Senior Scientist, Bioconjugates
• Function Discovery & Pre-Clinical/Clinical Development
• Sub function Biotherapeutics R&D
• Category Senior Scientist, Biotherapeutics R&D (ST6)
• Location Spring House / United States of America
• Date posted Aug 21 2025
• Requisition number R-028473
• Work pattern Fully Onsite

This job posting is anticipated to close on Sep 19 2025. We may however extend this time period, in which case the posting will remain available on www.careers.jnj.com to accept additional applications.

Description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biotherapeutics R&D

Job Category:

Scientific/Technology

All Job Posting Locations:

Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine:

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at

We are searching for the best talent for a Senior Scientist, Bioconjugates role to be in Spring House, PA.

Purpose:

The Bioconjugates group within Global Discovery Chemistry is a part of Therapeutics Discovery at J&J IM and is engaged in developing novel therapeutics across bioconjugate modalities including Antibody-drug Conjugates (ADCs), Radioligand Therapies (RLTs), and siRNA conjugates.

We are looking for a talented, highly motivated, and technically proficient Antibody Conjugate scientist to become part of our team. The successful candidate will have a background in bioconjugate chemistry, antibody discovery, protein chemistry, or a related field with a record of developing new technologies and achieving research goals on aggressive timelines through effective cross-functional collaboration. They should have experience in discovery or development of targeted therapeutics such as ADCs, peptide/small molecule conjugates, or nucleic acid conjugates (siRNA, antisense, etc.) as well as analytical characterization of these products.

You will be responsible for:

• designing and executing new project ideas (design and execution of studies, analysis of data, presentation of results) to support multiple research programs and provide critical data to inform decisions in a cross-functional team.
• collaborating with the therapeutic areas and other groups to define strategies and deliver stage-appropriate molecules for preclinical studies.
• keeping abreast of new technologies/capabilities relevant to this role and strive to implement them to advance research projects.
• authoring data summaries, technical reports, publications, and presentations.

Qualifications / Requirements:

Education:

• a minimum of a Bachelor's degree in Chemistry, Biochemistry, Chemical/Biomedical Engineering, or other related field is required
• a PhD is preferred

Required:

• a minimum of 4 years relevant research experience performing progressively advanced duties is required
• experience with biomolecule purification using automated chromatography systems is required.
• being organized, self-motivated and capable of working independently in a collaborative multi-disciplinary environment is required
• A solid research record demonstrated by patents, publications, or presentations.
• Excellent oral and written communication skills is required
• Interest and ability to work in a dynamic, fast-paced environment, and be capable of handling multiple tasks while meeting timelines is required
• Ability to lead projects and work productively in an interdisciplinary team environment is required
• Flexibility to adjust priorities over time to meet deadlines is required

Preferred:

• experience with bioconjugation methods, protein biochemistry, and/or peptide chemistry is preferred.
• experience with LC/MS characterization of large molecules is preferred.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (...) or contact AskGS to be directed to your accommodation resource.