Senior Scientist

  • Cynet Systems
  • Cambridge, Massachusetts
  • Full Time


Pay Range: $67.02hr - $72.02hr
  • Responsible for designing and performing in vivo pharmacology experiments in support of project team goals.
  • This includes study design, data collection and recording, communication of results, and report writing.
  • Summarize and present study data to project teams within established timelines.
  • Generate specific pharmacology reports based on studies performed to support IND submission.
  • Capacity to use established procedures and methodologies with the ability to transform novel approaches into routine practice.
  • Use detailed knowledge of state-of-the-art tools and approaches to enhance in vivo evaluation of novel therapeutics' mechanisms of action and/or identify new targets.
  • Identify and develop ex vivo analytical tools that can be used to maximize the read-outs from in vivo studies.
  • Must be a technical contributor.
  • Ability to troubleshoot experiments.
  • Support the development of disease relevant in-vivo models.
  • Must be well-organized and detail-oriented.
  • Must have meticulous record-keeping skills according to quality guidelines.
  • Maintain a thorough and compliant laboratory notebook.
  • Must adhere to all federal, local, and animal welfare guidelines.
  • Must be capable of working alone and in a team environment.
Qualifications:
  • Deep knowledge of immunology, a mechanistic understanding of autoimmune or inflammatory pathologies.
  • Proficiency in establishing in vivo PK/PD and efficacy models of immunology/autoimmune diseases (e.g., DClient, DSS, T cell transfer model, ovalbumen-induced asthma ).
  • Extensive in vivo pharmacology expertise in working with rodent inflammatory models and in molecular, cellular biology, and immunological assays (e.g, Flow cytometry, cytokine measurement) required.
  • Well-established hands-on experience with in vivo dosing, bleeding, and handling techniques, and proficiency in basic surgical techniques.
  • Experience with compound or reagent preparation.
  • Ability to work under moderate supervision with regular review of results and methods utilized.
  • Ability to present study-related results to project teams.
  • Proven ability to work in a dynamic, customer-focused, and results-oriented environment.
Education and Experience:
  • Master s Degree plus a minimum of 3 years of relevant research experience in a biopharmaceutical setting OR a Ph.D. in Immunology, Pharmacology with 1 year of relevant research experience in an academic facility or biopharmaceutical setting.
Job ID: 490731482
Originally Posted on: 8/26/2025

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