Bioanalytical LC-MS Scientist

Role Description

Zoetis Veterinary Medicine Research and Development (VMRD) seeks an enthusiastic colleague for a challenging and fast-paced position in research and development of veterinary medicines in Kalamazoo, Michigan. As an integral member of research and development project teams, the candidate will support studies to understand the absorption, distribution, metabolism, and elimination of veterinary pharmaceuticals in food producing animals with a goal of demonstrating the safety of food products intended for human consumption. The candidate will collaborate with bioanalytical, target animal safety, toxicology, pharmacokinetics, environmental, clinical, and regulatory scientists as part of a multidisciplinary team.

Responsibilities include :

Developing and validating robust analytical methods to quantify residues of veterinary pharmaceuticals and biotherapeutics in blood/plasma, tissues, excreta, and other matrices at the low ng/g to pg/g level.

Assisting with study designs and protocol development for in vitro and in vivo studies.

Collaborating with other VMRD groups and partners to provide high quality and seamless support for projects.

Serving as sample analyst for GLP studies.

Writing or contributing to study reports and regulatory submissions.

Participate in continuous improvement and innovation efforts within the Global Therapeutics, Clinical Pharmacology & Safety Sciences residue group.

Occasional domestic professional travel.

Minimum skills, education, & attributes :

BS or MS in chemistry, biochemistry, biology, pharmaceuticals, or a related field.

BS/MS with at least 3-6 years of experience in the veterinary or human pharmaceutical, or agricultural/food industry.

Experience developing de novo analytical methods for new chemical entities in biomatrices by UHPLC-MS/MS and other methods.

Experience in preparation methodologies for biomatrices.

Excellent written and oral communication abilities (verbal and written English).

Ability to work in a collaborative and dynamic team environment in a global company.

Desirable skills, education, & attributes :

Working in a regulated environment (e.g., GLP).

Working with radioisotopes (14C, 3H).

In vitro metabolism or in vivo ADME studies.

Working with E-notebooks, LIMS, laboratory automation, and liquid handling systems.

Familiar with regulatory requirements (e.g., VICH/ICH, FDA/CVM, OECD) for human or veterinary pharmaceuticals.

Full timeRegularColleague

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