Senior Scientist, Chemistry and Delivery

The Role
We are looking for an accomplished Scientist to spearhead the development of targeted lipid nanoparticle (LNP) formulations within our fast-moving, cross-functional R&D organization. In this role you will push the boundaries of LNP self-assembly, engineer delivery systems for both small- and large-molecule payloads beyond the liver and apply state-of-the-art analytical techniques to link structure with biological performance.

Here's What You'll Do

* Drive research programs on targeted, extra-hepatic LNP delivery-from hypothesis generation through in-vitro / in-vivo evaluation

* Develop and optimize LNP self-assembly processes; refine composition, payload loading, and surface modifications for tissue and cell-type specificity

* Independently Design and execute experiments; analyze, interpret, and clearly communicate data to multidisciplinary project teams and leadership

* Implement and innovate advanced physicochemical and biophysical characterization methods (e.g., DLS, CryoEM, SAXS, ITC, NMR, nFCM etc) to elucidate structure-function relationships

* Maintain rigorous electronic laboratory notebooks, SOPs, and study documentation consistent with company expectations

* Mentor & collaborate with research associates, and external partners to meet project milestones

Here's What You'll Need (Basic Qualifications)

* Ph.D. in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Materials Science, or a related discipline with 2+ years of experience.

* Deep expertise in lipid nanoparticle design, formulation, and characterization; hands-on experience developing targeted or extra-hepatic LNPs preferred

* Proficiency with a broad suite of analytical techniques for nanoparticle size, morphology, composition, and stability assessment

* Demonstrated ability to plan and manage multiple projects in a highly collaborative, fast-paced setting

* This position is site-based, requiring you to be at Moderna's site full-time. This position is not eligible for remote work

Here's What You'll Bring to the Table (Preferred Qualifications)

* Ph.D. in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Materials Science, or a related discipline with 2+ years of experience.

* Deep expertise in lipid nanoparticle design, formulation, and characterization; hands-on experience developing targeted or extra-hepatic LNPs preferred

* Proficiency with a broad suite of analytical techniques for nanoparticle size, morphology, composition, and stability assessment

* Demonstrated ability to plan and manage multiple projects in a highly collaborative, fast-paced setting

* Clear, concise scientific communication-written and verbal-with a track record of peer-reviewed publications and/or patents

* Commitment to inclusive teamwork, continuous learning, and high scientific rigor

* Experience with high-throughput methodologies is highly desirable, and familiarity with artificial intelligence and machine learning techniques is considered a strong plus

Pay & Benefits

At Moderna, we believe that when you feel your best, you can do your best work. That's why our US benefits and global well-being resources are designed to support you-at work, at home, and everywhere in between.

* Best-in-class healthcare coverage, plus voluntary benefit programs
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