Scientist - In Vivo Pharmacology

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United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

Your Role:

EMD Serono in Billerica, MA, is seeking a Scientist- In Vivo Pharmacology. The In Vivo Pharmacology Scientist will be responsible for the hands-on execution of in vivo pharmacology studies that utilize mouse tumor models to study the anti-tumor activity of novel oncology and immuno-oncology agents. The Scientist will work both independently and collaboratively as part of an in vivo pharmacology team and will be responsible for study execution, data analysis and generation of electronic notebooks. The successful candidate will work efficiently with multiple projects and provide high-quality data package within project timelines.

Responsibilities:

• Independent planning and hands-on execution of in vivo pharmacology studies that utilize mouse tumor models for cancer therapy.
• Perform sample processing from multiple tissue sources for downstream analysis and support sample analysis.
• Maintenance of mammalian cell culture.
• Analyze and interpret data; prepare comprehensive technical reports, statistical analyses, and visualizations for internal stakeholders.
• Optimize and validate in vivo pharmacology assays and readouts (tumor models, PK/PD, biomarker readouts); troubleshoot and propose alternative experimental designs, controls, and readouts as needed.
• Follow IACUC protocols and standard operating procedures (SOPs); maintain detailed records of experimental protocols and data in an electronic laboratory notebook in accordance with company policy.

Who You Are:

Minimum Qualifications:

• Master's degree in Biology, Pharmacology, Oncology, Immunology, or other Life Science discipline with 3+ years of hands-on experience with administering compounds via various routes (PO, IV, IP, SC) and blood/tissue collection

OR

• Bachelor's degree in Biology, Pharmacology, Oncology, Immunology, or other Life Science discipline with 5+ years of hands-on experience with administering compounds via various routes (PO, IV, IP, SC) and blood/tissue collection
• 3+ years of experience with mammalian cell culture

Preferred Qualifications:

• Experience with mouse models of cancer, including tumor cells implantation and tumor measurements
• Proficiency in data collection/documentation of all study results in the form of lab notebook reports and, as needed, contribution to the authorship of regulatory submission documents
• Understanding and previous experience with immunological readouts, E.g., FACS-based immunophenotyping, cytokine profiling (multiplex assays), assessment of tumor immune infiltrates, and functional assays (ELISPOT, cytotoxicity assays)
• Experience with patient-derived xenograft (PDX) models and humanized mouse models
• Hands-on experience conducting small animal research studies involving image guided radiation or live imaging (e.g. micro-CT, IVIS imaging, MRI)
• Strong statistical and data visualization skills; proficiency with software such as GraphPad Prism, R, or Python for data analysis
• Strong written and oral communication skills, interpersonal skills and ability to effectively work as part of a team

Pay Range for this position: $96,600 - $159,600

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!