Research Lab Technician Senior

This posting is for a Research Technician Senior position in the Division of Cardiovascular Medicine at the University of Michigan. Our laboratory investigates cardiovascular inflammation and remodeling using murine models of myocardial infarction and heart failure. The successful candidate will join a collaborative research team focused on high-dimensional vascular and immune phenotyping, tissue harvesting and processing, and in vivo model management. The role demands consistent technical execution, strong organizational skills, and close attention to animal welfare across complex, multi-cohort experimental designs.

• Perform injections, blood collection, perfusions, and tissue harvest with high precision and consistency across repeated procedures to minimize experimental variability
• Process heart tissue, spleen, bone marrow, and other organs using standardized cell isolation protocols
• Maintain detailed records of mice cohorts.
• Monitor animal health with strong situational awareness, recognizing subtle changes in posture, breathing, or behavior, and escalating concerns promptly
• Prepare samples for downstream analyses including flow cytometry, histology, sequencing, and proteomics.
• Follow and help maintain standardized laboratory protocols for perfusion, tissue digestion, blood collection, and related procedures
• Prepare reagents and organize surgical instruments in advance of harvest days to support efficient, error-free processing of large cohorts
• Communicate clearly and immediately about problems, uncertainty, or deviations from expected outcomes
• Maintain a well-organized inventory of laboratory materials and place order requests with the Internal Medicine Purchasing team
• Attend scheduled laboratory meetings and contribute to discussions of experimental design and troubleshooting
• Analyze data for publications under the direction of the PI
• Other duties as assigned
  

• A bachelor's degree in a biological or health science discipline, with an advanced degree or additional training preferred
• Previous experience in a bench science research laboratory is required
• Demonstrated ability to perform repeated procedures (such as injections, tissue harvest, or sample processing) with precision and consistency
• Experience with phenotyping animal models, RNA and protein extraction protocols, cell culture, and molecular biology techniques (e.g. quantitative PCR, next-generation sequencing)
• Ability to maintain detailed, accurate records of experiments and mouse cohorts across multiple concurrent studies
• Effective written and verbal communication skills, including the ability to report problems or uncertainty promptly
• Comfort with online project management tools and communication platforms
• Flexibility to conduct experiments over some weekends as needed
• Understands and demonstrates the core concepts of Patient and Family Centered Care, including Respect and Dignity, Information Sharing, Participation, and Team Collaboration
  

• A background in immunology and/or vascular biology
• Experience with organ processing and cell isolation from murine models, particularly heart, spleen, vascular tissues, and bone marrow
• Demonstrated commitment to continuous skill development, including willingness to take on advanced responsibilities such as managing large cohorts, training new staff, or preparing samples for sophisticated analyses
• Familiarity and openness toward project management tools and communication platforms
  

We, the staff and faculty of the U-M Cardiovascular Center (CVC) team, are dedicated to advancing medicine and serving humanity by living and teaching our core values of Respect and Compassion; Collaboration; Innovation; and Commitment to Excellence. Every CVC employee is expected to understand and demonstrate that in all interactions, we represent our entire organization through the quality of care we provide and the courtesies we extend to patients, families, and team members. The CVC is committed to partnering with patients and families to deliver the safest and highest quality health care.

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

The University of Michigan is an equal employment opportunity employer.