Scientist 1 Protein Engineering & Manufacturing
- OriGene Technologies, Inc.
- Frederick, Maryland
- Full Time
Scientist 1 - Protein Engineering & Manufacturing
OriGene Technologies, Inc.
Post Date : May 23, 2025 Before : Jun 23, 2025 0 18
:
Job Detail
Offered Salary
0
Commitment
Full Time
Compensation
Paid
Required education level
Master's degree
Job Description
Requirements
The ideal candidate will have an industrial background, with experience in IVD product development and a strong understanding of biotech research markets. A business- and marketing-oriented mindset is essential to align scientific innovation with customer needs and product positioning. In addition to technical responsibilities, this role may support technology transfer, regulatory submissions, and strategic planning in collaboration with other internal departments, including commercial and product management teams.
Responsibilities and Job Duties
Contribute to rational protein engineering projects; analyze protein structures and properties to design antigens for antibody and diagnostic reagent development.
Perform recombinant protein expression, purification, formulation, and physical characterization using multiple systems (e.g., E. coli, insect, mammalian).
Support IVD-related product development and ensure compliance with quality and regulatory standards.
Collaborate cross-functionally with antibody, assay, clone, CRISPR, pathology reagent, lentiviral/AAV, and cell therapy R D teams to drive innovation and expand the product pipeline.
Maintain a strong understanding of emerging science and technologies in the biomedical and diagnostic industries.
Engage in scientific discussions with collaborators and clients to evaluate current products, support ongoing projects, and identify new opportunities.
Develop and optimize SOPs and validation protocols; provide on-site technical guidance and training for research associates.
Communicate with customers to understand and fulfill custom protein and antibody project requirements.
Coordinate with sales, marketing, new product development and technical support teams to promote products, support order fulfillment, and resolve product-related issues.
Prepare and present technical reports, data summaries, and presentations for both internal teams and external stakeholders.
Prepare scientific posters, abstracts, and presentations; represent the company at relevant scientific conferences and industry meetings.
Perform routine maintenance and troubleshooting of lab equipment and instrumentation.
Qualifications
Education & Experience
Master's degree with 5-8 years of experience, or Ph.D. with 3-5 years of post-graduate experience in biology, biochemistry, molecular biology, or a related life science field.
Industrial experience required; experience with clinical diagnostic product development and regulatory awareness is strongly preferred.
Proven expertise in recombinant protein expression and purification from various heterologous systems (bacteria, yeast, insect, and mammalian).
Skilled in using liquid chromatography systems (e.g., AKTA) and a variety of separation matrices (e.g., SEC, IEX, HIC).
Proven ability to independently troubleshoot protein construct design in order to optimize protein expression and purification using various purification tags (His6, FLAG, MBP, GST, etc.)
Experience with protein formulation and analytical techniques (e.g., analytical SEC, BLI, DSF, ELISA).
Proficiency with structural modeling tools (e.g., PyMOL, Schrodinger, MOE, Rosetta) and structural-based protein engineering.
Familiarity with antibody or cell-based functional assays is a plus.
Practical experience with cell/molecular biology techniques such as PCR, mutagenesis, DNA/RNA extraction, western blotting, aseptic cell culture, and flow cytometry.
Knowledge, Skills, and Abilities
Strong analytical and problem-solving skills with the ability to work independently and collaboratively.
Demonstrated success in cross-functional teamwork and project coordination across research, development, and business functions.
Understanding of the biotech market landscape with the ability to align product development with customer needs and business strategy.
Strong organizational and time management skills with the ability to handle multiple complex projects in a fast-paced environment.
Effective communicator with excellent written and oral communication skills; ability to convey technical information clearly to both scientific and non-scientific audiences.
Proficient in Microsoft Office tools (Word, Excel, PowerPoint, Outlook) and scientific data analysis tools (e.g., GraphPad Prism, Photoshop, DNAStar).
Application ends in 29d 6h 39min
Scientist 1 - Protein Engineering & Manufacturing
OriGene Technologies, Inc.
Post Date : May 23, 2025 Before : Jun 23, 2025 0 18
:
OriGene Technologies, Inc.
Post Date : May 23, 2025 Before : Jun 23, 2025 0 18
:
Job Detail
Offered Salary
0
Commitment
Full Time
Compensation
Paid
Required education level
Master's degree
Job Description
Requirements
The ideal candidate will have an industrial background, with experience in IVD product development and a strong understanding of biotech research markets. A business- and marketing-oriented mindset is essential to align scientific innovation with customer needs and product positioning. In addition to technical responsibilities, this role may support technology transfer, regulatory submissions, and strategic planning in collaboration with other internal departments, including commercial and product management teams.
Responsibilities and Job Duties
Contribute to rational protein engineering projects; analyze protein structures and properties to design antigens for antibody and diagnostic reagent development.
Perform recombinant protein expression, purification, formulation, and physical characterization using multiple systems (e.g., E. coli, insect, mammalian).
Support IVD-related product development and ensure compliance with quality and regulatory standards.
Collaborate cross-functionally with antibody, assay, clone, CRISPR, pathology reagent, lentiviral/AAV, and cell therapy R D teams to drive innovation and expand the product pipeline.
Maintain a strong understanding of emerging science and technologies in the biomedical and diagnostic industries.
Engage in scientific discussions with collaborators and clients to evaluate current products, support ongoing projects, and identify new opportunities.
Develop and optimize SOPs and validation protocols; provide on-site technical guidance and training for research associates.
Communicate with customers to understand and fulfill custom protein and antibody project requirements.
Coordinate with sales, marketing, new product development and technical support teams to promote products, support order fulfillment, and resolve product-related issues.
Prepare and present technical reports, data summaries, and presentations for both internal teams and external stakeholders.
Prepare scientific posters, abstracts, and presentations; represent the company at relevant scientific conferences and industry meetings.
Perform routine maintenance and troubleshooting of lab equipment and instrumentation.
Qualifications
Education & Experience
Master's degree with 5-8 years of experience, or Ph.D. with 3-5 years of post-graduate experience in biology, biochemistry, molecular biology, or a related life science field.
Industrial experience required; experience with clinical diagnostic product development and regulatory awareness is strongly preferred.
Proven expertise in recombinant protein expression and purification from various heterologous systems (bacteria, yeast, insect, and mammalian).
Skilled in using liquid chromatography systems (e.g., AKTA) and a variety of separation matrices (e.g., SEC, IEX, HIC).
Proven ability to independently troubleshoot protein construct design in order to optimize protein expression and purification using various purification tags (His6, FLAG, MBP, GST, etc.)
Experience with protein formulation and analytical techniques (e.g., analytical SEC, BLI, DSF, ELISA).
Proficiency with structural modeling tools (e.g., PyMOL, Schrodinger, MOE, Rosetta) and structural-based protein engineering.
Familiarity with antibody or cell-based functional assays is a plus.
Practical experience with cell/molecular biology techniques such as PCR, mutagenesis, DNA/RNA extraction, western blotting, aseptic cell culture, and flow cytometry.
Knowledge, Skills, and Abilities
Strong analytical and problem-solving skills with the ability to work independently and collaboratively.
Demonstrated success in cross-functional teamwork and project coordination across research, development, and business functions.
Understanding of the biotech market landscape with the ability to align product development with customer needs and business strategy.
Strong organizational and time management skills with the ability to handle multiple complex projects in a fast-paced environment.
Effective communicator with excellent written and oral communication skills; ability to convey technical information clearly to both scientific and non-scientific audiences.
Proficient in Microsoft Office tools (Word, Excel, PowerPoint, Outlook) and scientific data analysis tools (e.g., GraphPad Prism, Photoshop, DNAStar).
Application ends in 29d 6h 39min
Scientist 1 - Protein Engineering & Manufacturing
OriGene Technologies, Inc.
Post Date : May 23, 2025 Before : Jun 23, 2025 0 18
:
Job ID: 478545299
Originally Posted on: 5/26/2025
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