Senior Associate Scientist, Investigative Sciences

Support a variety of investigative, mechanistic siRNA research efforts to evaluate RNAi compounds by applying various biochemistry and cell/molecular biology assays. Quantify siRNA/mRNA/protein using various assays (qPCR, Western blotting, ELISA, immunoprecipitations, imaging). Contribute and support endpoint analyses for in vivo studies. A willingness to learn and execute new techniques to support in vitro and in vivo studies. Routinely adapt/change assays, troubleshoot, and interpret experiments. Prepare clearly articulated experimental results and present for a variety of audiences. BS/MS in Biology, Cell/Molecular Biology, Biochemistry or related field with 3-5 years of work experience, preferably in a field of oligonucleotides. Experience in mammalian cell culture and molecular biology assays for RNA/DNA/protein quantification. Excellent lab technique and ability to work independently. Strong interpersonal and communication skills (written and oral) are required. Excellent organization, documentation, and record-keeping are required. Familiarity with oligonucleotides (e.g., siRNA, ASO, mRNA, or CRISPR) is desirable.