Principal scientist, Data Scientist, Clinical Pathology & Safety Biomarkers

• Job title Principal scientist, Data Scientist, Clinical Pathology & Safety Biomarkers
• Function Discovery & Pre-Clinical/Clinical Development
• Sub function Nonclinical Safety
• Category Principal Scientist, Nonclinical Safety (ST7)
• Location Spring House / La Jolla / United States of America
• Date posted Jun 04 2025
• Requisition number R-009193
• Work pattern Fully Onsite

This job posting is anticipated to close on Jun 11 2025. We may however extend this time period, in which case the posting will remain available on www.careers.jnj.com to accept additional applications.

Description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Nonclinical Safety

Job Category:

Scientific/Technology

All Job Posting Locations:

La Jolla, California, United States of America, Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine:

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at

We are searching for the best talent for a Principal scientist, Data Scientist, Clinical Pathology & Safety Biomarkers to be in Spring House, PA and La Jolla, CA.

Purpose:

The Clinical Pathology & Safety Biomarkers (CPSB), Pathobiology, Preclinical Sciences and Translational Safety (PSTS), is seeking a highly motivated Principal Scientist to develop and conduct data analytics, visualization, and application of Artificial Intelligence/Machine Learning approaches in the CPSB laboratory. The CPSB laboratory is a team of medical laboratory and biomarker scientists responsible for delivering on the PSTS translational safety biomarker vision of end-to-end (efficacy-to-safety, Discovery through Post-Marketing) across all J&J modalities and therapeutic areas.

The Principal Scientist will be responsible for applying data science approaches to analyze complex data-sets to drive key insights and support translational biomarker strategies. The candidate will need to have a breadth of skills and knowledge to address key biological concerns and portfolio needs into meaningful data science questions and approaches to deploy relevant data analytics and visualization techniques. The candidate is intellectually curious and will thrive in a dynamic, multidisciplinary and collaborative environment. This role reports to the Translational Biomarker lead of the CPSB team.

You will be responsible for:

• Working closely with internal stakeholders (within CPSB and Pathobiology) and external partners (Scientific & In Vivo Strategies and Technology Research Systems) to understand and prioritize use cases and implement our Data Science roadmap for prioritized data science initiatives.
• Building a robust data infrastructure by cleaning, optimizing, and strategically defining clinical pathology and biomarker data management practices.
• Automating the transfer, aggregation, curation and connection of clinical pathology and biomarker data and relevant study data and metadata from diverse sources, handling various file types and formats.
• Developing and deploy data science solutions, including data processing, database programming, algorithm development, data visualization, , and communication of insights to PSTS partners
• Building of custom pipelines/apps for big data analysis, bioinformatics, statistical modelling and biological interpretations of in vivo study data
• Providing leadership in Data Science management practices, fostering a data-driven culture, applying innovative approaches, and ensuring data compliance
• Provide expertise and mentorship on data science methodologies
• Conducting quality control checks to ensure accuracy of data and data integrity compliance
• Communicating data workflows and solutions to stakeholders
• Collaborating, presenting, and communicating project-related deliverables in multidisciplinary team meetings that include pathologists, immunotoxicologists, and nonclinical safety leads

Qualifications / Requirements:

Education:

• a minimum of a Master's degree in Biology or related field with programming and data science expertise or in Computer Science, Statistics, Engineering, Science, Data Science, or applicable quantitative field with experience in biology is required
• a PhD is highly preferred

Required:

• A minimum of 6 years Data Science experience in an industry or academic setting post-degree in positions of increasing responsibility is required
• Expertise in data visualization and dashboarding (e.g. Excel, Spotfire, Tableau, PowerBI, R-Shiny) is required
• Good knowledge of SAS, Python, or R programming, is required
• Strong track record and ability to work independently is required
• Analytical mind-set, intellectual curiosity, eagerness for continuous learning and passion for translating data into applied solutions is required
• Excellent interpersonal skills are required

Preferred:

• Experience in Biology, Biotechnology, In Vitro Diagnostic, or Health Care industries is preferred
• Proficient in Python/R/Alteryx programming and experienced with Data Science Cloud platforms like Amazon, Snowflake, and Domino is preferred
• Experience and proficiency in the use of statistical models, including (but not limited to) multivariate linear regression, cluster algorithms, decision trees, logistic regression, Principal Component Analysis (PCA), machine learning (supervised and unsupervised), Bayesian Methods, Neural Networks etc is preferred
• Knowledge of medical terminology and familiarity with biological research is preferred
• Understanding and proficiency in laboratory-based in vitro techniques including molecular techniques (e.g. PCR) and immunoassays (e.g. ELISA) is preferred

The anticipated base pay range for this position is $115,000 - $197,800

The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation's performance over a calendar/performance year. Bonuses are awarded at the Company's discretion on an individual basis.

• Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.

• Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).

• This position is eligible to participate in the Company's long-term incentive program.

• Employees are eligible for the following time off benefits:

• Vacation - up to 120 hours per calendar year

• Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year

• Holiday pay, including Floating Holidays - up to 13 days per calendar year

• Work, Personal and Family Time - up to 40 hours per calendar year

Additional information can be found through the link below.

For additional general information on Company benefits, please go to:

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (...) or contact AskGS to be directed to your accommodation resource.

The anticipated base pay range for this position is :

$115,000 - $197,800

Additional Description for Pay Transparency: