Staff Scientist I- Antibody Reagent and Discovery

If you are a highly skilled bench Scientist in research with a background in immunology, take your career to the next level at Labcorp as a Staff Scientist I - Antibody Reagent and Discovery and join our growing team in Denver, PA (relocation assistance available) . Labcorps work in developing new pharmaceutical solutions has an incredible impact on the lives of millions of patients worldwide, helping transform great science into great medicines. Be a part of this life-saving work!

This position offers the opportunity to contribute to cutting-edge research in the development of immune therapeutics in a collaborative and innovative environment.

Position Summary:

We are seeking an experienced and highly skilled Staff Scientist to join our team, focusing on antibody reagents generation and discovery services. The ideal candidate will have a strong background in antibody-based reagents to support diagnostic and therapeutic programs, as well as a strong understanding of trends in monoclonal antibody therapeutic discovery and development. This role requires hands-on experience in immunization strategies, hybridoma/B cell cloning and display technologies, antibody characterization, and assay development.

Key Responsibilities:

• Execute and oversee antibody and antibody variant (e.g., Fab, scFv, full-length IgG) generation and purification campaigns.

• Contribute to the development and optimization of antigen preparation strategies (e.g., recombinant protein expression eukaryotic and mammalian systems).

• Perform and contribute to hybridoma and singe B cell cloning methods for monoclonal antibody campaigns.

• Characterize binding specificity, affinity, and cross-reactivity of antibody reagents using ELISA, SPR/BLI and other immunoassays.

• Analyze complex data, prepare reports, and present findings to internal and external stakeholders.

• Mentor and lead junior scientists and provide guidance in assay development, data interpretation, and troubleshooting.

• Collaborate with other groups within Labcorp to ensure seamless integration of ARV services into product development programs

• Stay current with scientific advances in antibody discovery and reagent technologies.

Education and Qualifications:

• Ph.D. in Immunology or related biological science with a strong focus on antibody-based research.

• A minimum of 2-5 years of industry experience in antibody-based studies for therapeutics.

• Extensive hands-on experience in the development, optimization, and validation of antibodies (e.g., AKTA FPLC purification, Meso Scale Discovery and other immune-based techniques).

• Demonstrated ability to lead and manage complex scientific projects and multidisciplinary teams.

• Excellent communication skills with the ability to convey complex scientific concepts to both technical and non-technical stakeholders.

• Proficiency in using scientific software and laboratory automation tools.

Preferred Skills:

• Experience with gene therapies, biosimilars, display technologies or novel biologics.

• Knowledge of regulatory guidance for Anti-Drug Antibody and PK testing for biologics.

• Experience with assay development in a GLP environment.

Pay Range: $85k-$105k annually (USD)

All job offers will be based on a candidates skills and prior relevant experience, applicable degrees/certifications, as well as internal equity and market data.

Benefits: Employees regularly scheduled to work 20 or more hours per week are eligible for comprehensive benefits including: Medical, Dental, Vision, Life, STD/LTD, 401(k), Paid Time Off (PTO) or Flexible Time Off (FTO), Tuition Reimbursement and Employee Stock Purchase Plan. Casual, PRN & Part Time employees regularly scheduled to work less than 20 hours are eligible to participate in the 401(k) Plan only. For more detailed information, please click here .

Labcorp is proud to be an Equal Opportunity Employer:

Labcorp strives for inclusion and belonging in the workforce and does not tolerate harassment or discrimination of any kind. We make employment decisions based on the needs of our business and the qualifications and merit of the individual. Qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, or related medical conditions), family or parental status, marital, civil union or domestic partnership status, sexual orientation, gender identity, gender expression, personal appearance, age, veteran status, disability, genetic information, or any other legally protected characteristic. A dditionally, all qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law.

We encourage all to apply

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