Research Associate II
South San Francisco, CA
Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas!
Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at astellas .
Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians.
If you want to be part of this exciting work, you belong at Astellas!
Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at astellas .
The Role:
The Research Associate II will work onsite with the lead scientist for cellular assays including AAV potency, infectivity and cytotoxicity to support teams including the GT Engineering.
Responsibilities:
Perform mammalian cell culture and DNA/siRNA transfection, AAV infection/transduction.
Perform DNA and RNA isolation, PCR, qPCR and ddPCR analysis of gene expression.
Perform Western Blot, ELISA, etc to evaluate protein expression and function.
Perform other cell based functional assays.
Collect, process, and evaluate data; accurately document assay results and analyze data, prepare study reports, and communicate results and research progress in lab meetings as needed.
Participate in sample management activities such as receiving, processing, storage, and shipping pre-clinical samples.
Collaborate with other teams to efficiently handle material and data transfer between groups
Required Qualifications
Bachelor's degree in Biology, Cell Biology, Molecular Biology, or Biochemistry with 2+ years of wet lab experience
Proven proficient hands-on experience with sterile technique for handling and maintaining mammalian cells.
Demonstrated experience with cellular techniques (2D & 3D cell culture, expansion, maintenance, characterization, differentiation, banking).
Demonstrated protein based assays including but not limited to protein expression level, modification, protein binding/interaction, enzymatic evaluation.
Ability to work both independently and in a team-oriented environment to meet project goals and timelines
Strong written and verbal communication skills.
Preferred:
Broad understanding of cell biology, molecular biology and biochemistry assays.
Fast learner with Passion to improve the work efficiency and quality.
Intensive wet lab experience handling and growing mammalian cells including cell lines, primary cells.
Ability to set up cell based functional assays.
Experience working with viruses, especially Adeno-Associated Virus (AAV).
Work Environment:
This position is based in South San Francisco, CA, USA and will require on-site work
Salary Range: $67,200- $96,000 (NOTE: Final salary could be more or less, based on experience)
Benefits:
Medical, Dental and Vision Insurance
Generous Paid Time Off options, including Vacation, Sick time, plus national holidays including Heritage Days, and Summer and Winter Breaks
401(k) match and annual company contribution
Company paid life insurance
Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
Long Term Incentive Plan for eligible positions
Referral bonus program
All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, sexual orientation, gender identity, national origin, protected veteran status, or on the basis of disability.
#LI-TR1
Category GT - Discovery Bioscience
Astellas is committed to equality of opportunity in all aspects of employment.
EOE including Disability/Protected Veterans
South San Francisco, CA
Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas!
Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at astellas .
Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians.
If you want to be part of this exciting work, you belong at Astellas!
Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at astellas .
The Role:
The Research Associate II will work onsite with the lead scientist for cellular assays including AAV potency, infectivity and cytotoxicity to support teams including the GT Engineering.
Responsibilities:
Perform mammalian cell culture and DNA/siRNA transfection, AAV infection/transduction.
Perform DNA and RNA isolation, PCR, qPCR and ddPCR analysis of gene expression.
Perform Western Blot, ELISA, etc to evaluate protein expression and function.
Perform other cell based functional assays.
Collect, process, and evaluate data; accurately document assay results and analyze data, prepare study reports, and communicate results and research progress in lab meetings as needed.
Participate in sample management activities such as receiving, processing, storage, and shipping pre-clinical samples.
Collaborate with other teams to efficiently handle material and data transfer between groups
Required Qualifications
Bachelor's degree in Biology, Cell Biology, Molecular Biology, or Biochemistry with 2+ years of wet lab experience
Proven proficient hands-on experience with sterile technique for handling and maintaining mammalian cells.
Demonstrated experience with cellular techniques (2D & 3D cell culture, expansion, maintenance, characterization, differentiation, banking).
Demonstrated protein based assays including but not limited to protein expression level, modification, protein binding/interaction, enzymatic evaluation.
Ability to work both independently and in a team-oriented environment to meet project goals and timelines
Strong written and verbal communication skills.
Preferred:
Broad understanding of cell biology, molecular biology and biochemistry assays.
Fast learner with Passion to improve the work efficiency and quality.
Intensive wet lab experience handling and growing mammalian cells including cell lines, primary cells.
Ability to set up cell based functional assays.
Experience working with viruses, especially Adeno-Associated Virus (AAV).
Work Environment:
This position is based in South San Francisco, CA, USA and will require on-site work
Salary Range: $67,200- $96,000 (NOTE: Final salary could be more or less, based on experience)
Benefits:
Medical, Dental and Vision Insurance
Generous Paid Time Off options, including Vacation, Sick time, plus national holidays including Heritage Days, and Summer and Winter Breaks
401(k) match and annual company contribution
Company paid life insurance
Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
Long Term Incentive Plan for eligible positions
Referral bonus program
All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, sexual orientation, gender identity, national origin, protected veteran status, or on the basis of disability.
#LI-TR1
Category GT - Discovery Bioscience
Astellas is committed to equality of opportunity in all aspects of employment.
EOE including Disability/Protected Veterans
Job ID: 482055184
Originally Posted on: 6/20/2025
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