Senior Scientist - Biologics

Are you passionate about making the world better? Are you looking for an organization that aligns with your values?
MRIGlobal solves challenging problems through science, engineering, and program management. We are an independent scientific research organization dedicated to benefiting society and fostering a safe, healthy, and sustainable environment.
When you embark on a career with MRIGlobal, you are joining a crew of world-class talent and problem solvers. Established in 1944, MRIGlobal is headquartered in Kansas City, MO, working in several states including Virginia and Maryland.

Senior Scientist – Biologics

MRIGlobal is seeking a highly motivated individual to join our Integrated Pharmaceutical Solutions Business Unit as a Senior Scientist specializing in biologics development and analysis . This position is on-site at our headquarters in Kansas City, MO. The successful candidate will be part of a dynamic team supporting drug substance (DS) and drug product (DP) development for biologics, including vaccines, mAbs, gene therapies, and other advanced modalities. The ideal candidate will possess substantial experience in analytical characterization, method development, molecular biology, and technical leadership within the biopharmaceutical industry.

Principal Accountabilities and Success Factors

The Senior Scientist will play a key role in leading analytical activities to support the development, manufacturing, and release of biologics. The role requires strong technical expertise, project leadership skills, and the ability to work collaboratively across multidisciplinary teams. Successful candidates will demonstrate scientific rigor, adaptability, and the ability to contribute to technical strategy.

Duties may include but are not limited to the following:

• Lead the development, qualification, and execution of analytical methods for biologics, including proteins, plasmid DNA, viral vectors, and cell therapies.
• Perform technical reviews of analytical data, reports, and regulatory documents.
• Author and contribute to technical reports, protocols, regulatory submissions, and peer-reviewed publications with clear results and well-supported conclusions.
• Author technical sections of proposals for new work.
• Serve as subject matter expert (SME) in analytical method development and biologics characterization.
• Interact directly with clients to provide project updates, discuss data, and offer technical recommendations.
• Ensure compliance with regulatory guidelines (e.g., ICH, FDA, EMA) and MRIGlobal’s Quality Management System.

Minimum Qualifications

• M.S. in Analytical Chemistry, Biochemistry, Molecular Biology, or related field with a minimum of 6 years of biopharmaceutical industry experience; or a Ph.D. with at least 3 years of experience.
• Demonstrated experience in analytical method development and characterization of biologics (e.g., ELISA, PCR, HPLC, CE, mass spectrometry).
• Strong organizational and communication skills, with the ability to manage multiple projects simultaneously.
• Proficiency in common software tools (Word, Excel, PowerPoint, and scientific data analysis software).
• Applicants MUST be U.S. Citizens and eligible to obtain a Department of Defense Clearance.

Preferred Qualifications

• Expertise in critical quality attributes (CQA) determination for biologics, including identity, purity, potency, and safety testing.
• Familiarity with ICH Q2(R2) guidelines for method validation and qualification.
• Hands-on experience with advanced analytical techniques such as mass spectrometry (MS), qPCR, ELISA, cell based assays, and next-generation sequencing (NGS) for gene therapy products.
• Hands-on experience with lab-scale protein expression and cell culture.
• Experience managing client relationships and working in a contract research organization (CRO) or CDMO environment.
• Prior experience with technology transfer from R&D to GMP manufacturing.

Salary Range - $94,474 - $118,092

The salary range is intended as a general guideline and is not a guaranteed offer, as compensation depends on various factors such as scope and responsibilities of the position, candidate qualifications, experience, internal equity, and market conditions. MRIGlobal also provides a comprehensive benefits package, including health and life insurance, disability coverage, gym reimbursement, mental health support, paid holidays, and PTO.

WHAT WE OFFER
At MRIGlobal, we offer benefits and perks that make your life even better.

Your Well-Being: You can receive comprehensive coverage for you and your family, and resources that support mental, physical, social, and financial well-being. Get access to wellness benefits like virtual coaching, no-cost counseling, onsite health screenings, gym reimbursement, and more. MRIGlobal has received multiple wellness recognitions, including being named “Healthiest Employer” by Kansas City’s Business Journal in 2024.

A Bright Future: MRIGlobal offers award-winning employer retirement matches and no-cost financial education benefits. Get paid Parental Leave. Enjoy PTO, and a flexible culture that encourages work-life integration.

Personal Development: At MRIGlobal, you will enjoy diverse work that will grow your skillset, along with a tuition reimbursement option to pay for higher education.

A Genuine Community: MRIGlobal is a special workplace. From our Chili Cook-offs, Pi Day, and charitable giving opportunities, our traditions strengthen our team spirit. Join our seasonal staff events, DEI celebrations, and volunteer in initiatives that nurture future STEM generations.

To view all of MRIGlobal's current openings and to ensure that we receive your resume, visit our Career page.

EOE, including disability/vets. As an organization dedicated to scientific advancement, MRIGlobal invites and embraces diversity in our people. We value their unique backgrounds and perspectives in every aspect of our mission. We are committed to creating a safe, welcoming, and inclusive environment where everyone feels respected and represented, fostering a culture where all input is welcome. We adapt to change, challenge the status quo, and evolve through belonging, allyship, and mutual support.

Certain roles, depending on the nature of the job or work assignment require adherence to specific safety measures, including up-to-date vaccinations. This requirement aligns with both our operational needs and the expectations of our clients. Employees must furnish proof of such vaccinations before commencing their duties. Should an individual be unable to meet this vaccination criterion due to a legitimate medical condition, disability, pregnancy, or religious belief, we offer the option to apply for a reasonable accommodation in line with applicable laws. Inquiries or requests for accommodations should be directed to ... , ensuring a prompt and considerate resolution process. It's important to note that failure to comply with a vaccination-required role or to secure an approved accommodation may affect one's employment status with our organization.