Scientist, Translational ADME

• Job title Scientist, Translational ADME
• Function Discovery & Pre-Clinical/Clinical Development
• Sub function Pharmacokinetics & Pharmacometrics
• Category Scientist, Pharmacokinetics & Pharmacometrics (ST4 - E24)
• Location Spring House / United States of America
• Date posted Jun 24 2025
• Requisition number R-017907
• Work pattern Fully Onsite

This job posting is anticipated to close on Jul 02 2025. We may however extend this time period, in which case the posting will remain available on www.careers.jnj.com to accept additional applications.

Description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Pharmacokinetics & Pharmacometrics

Job Category:

Scientific/Technology

All Job Posting Locations:

Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at

We are searching for the best talent for Scientist, Translational ADME to be located in Spring House, PA.

Purpose: The Translational ADME In Vitro group is looking for a highly motivated Scientist to support drug discovery and development programs. Experience with sample preparation for analysis of radiolabeled compounds, LC-MS/MS analysis, and sample preparation using automated robotic platforms is desired. The ability to multitask and be flexible in a fast-paced environment is critical to this position. We are a highly motivated team, and our laboratories are state-of-the-art. As part of the global Translational ADME community within TPPIT, you will have access to a large arsenal of in silico, in vitro and in vivo tools and the vast expertise of colleagues at our various research sites in Belgium and the United States.

You will be responsible for:

• Mammalian cell culture including preparation of culture/assay media, cell culture maintenance, and preparation of cell-based assay plates to meet the demand of multiple concurrent projects.
• Support both the preclinical and clinical development organizations at J&J by performing transporter experiments based on established laboratory protocols and data processing procedures.

Qualifications

Education:

• Minimum of a Bachelor's Degree in (Molecular) Biology, Biotechnology or other related field is required.

Skills/Experience:

Required:

• Minimum of 3 year of relevant experience
• Experience in cell culture with proficient skills in standard mammalian cell culture procedures and associated aseptic techniques
• Ability to conduct drug transporter experiments based on established laboratory protocols and data processing including basic calculations and data analysis.
• Record keeping including electronic lab notebooks and all other pertinent documentation.

Preferred:

• Experience in quantitative mass spectrometry.
• A good understanding/Interest in DMPK relevant areas such as drug transporters and metabolizing enzymes, and pharmacokinetics.
• Experience with cell-based assays (e.g., cell monolayer efflux assay, cellular uptake assay) would be an asset.
• Experience in using laboratory equipment such as microplate readers, liquid scintillation counters and liquid handlers.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (...) or contact AskGS to be directed to your accommodation resource.