Senior Principal Scientist, Attribute Sciences Biophysical Characterization, Analytical Operations

Were here for one reason and one reason only to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. Weve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet.

Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows.

Job Description

Gilead's mission is to discover, develop, and deliver therapies that will improve the lives of patients with life-threatening illnesses

worldwide.

Reporting to Senior Director, Attribute Sciences, the Senior Principal Scientist, Attribute Sciences Biophysical Characterization, Analytical Operations will be responsible for leading a multi-disciplinary team that develops and utilizes state-of-the-art biophysical tools to assess product quality attributes that help guide process development and product knowledge of viral vector-based gene delivery platforms and T cell therapies.

In this role, the ideal candidate will lead the strategy for development of advanced biophysical analytics capabilities in Analytical Development, primarily Mass Spectrometry and extending to other technologies including Dynamic Light Scattering and Analytical Ultracentrifugation, among others, to understand the physical and chemical properties of vector and T cells. To be successful in this role, the ideal candidate must have extensive expertise in biophysical technologies to support process development, strategic thinking, business acumen, as well as excellent leadership skills.

Responsibilities include (but are not limited to):

• Guide the development strategy for the use of mass spectrometry techniques used to assess viral vector and cell therapy final product attributes

• Develop capabilities for in-house biophysical characterization of viral vectors (e.g., Dynamic Light Scattering, Sedimentation-Velocity Analytical Ultracentrifugation, Nanoparticle Tracking Analysis) to enhance viral vector product understanding.

• Supervise and develop scientists/analysts within Attributes Sciences

• Develop a high functioning team that is integrated in AD and cross-functionally to support business needs

• Support team members, hold them accountable for performance, coach/mentor as well as provide performance reviews of team members

• Enhance team capabilities to promote a diverse and complimentary analytical skill set to further process and product understanding

• Work collaboratively with Cell and Vector Attribute Sciences teams to inform product characterization and product knowledge strategies to advance pipeline programs

• Stay current with analytical technical platforms, cell and gene therapy industry best practices, as well as cutting edge innovations to support the development of cell therapy products

Qualifications

• Ph.D. in Biochemistry, Physical Chemistry, Molecular Biology or related discipline with 8+ years of industry experience or M.S. degree (M.S.) with 10+ years of industry experience

• Advanced knowledge of cell biology, cancer biology, and/or immunology preferred

• Extensive hands-on experience on the use of mass spectrometry for proteomics applications

• Experience performing biophysical analysis (e.g., Dynamic Light Scattering, Sedimentation-Velocity Analytical Ultracentrifugation, Nanoparticle Tracking Analysis) in scientific or technical environments to drive business solutions

• Proficiency in mass spectrometry and proteomics data analysis tools and methodologies, including interpretation and statistical analysis on large datasets

• Strong scientific writing and presentation skills

• Ability to think critically and demonstrate troubleshooting and problem-solving skills

• Highly collaborative with excellent interpersonal, verbal and written communication skills

• Self-motivated, detail-oriented, and willing to accept temporary responsibilities outside of initial job description

• Comfortable in a dynamic, fast-paced environment with minimal direction

• Demonstrated leadership ability in pharmaceutical manufacturing of biotechnology products, cell therapy products, analytical method development, and process development

• Agile mindset and ability to adjust workload based upon changing priorities

• Ability to work in, lead and foster cross-functional, collaborative teams

• Experience supporting, developing, and mentoring staff and creating inclusive, high-performing teams

• Ability to foster an organization that demonstrates integrity, accountability, teamwork, and excellence

People Leader Accountabilities:

Create Inclusion - knowing the business value of diverse teams, modeling inclusion, and embedding the value of diversity in the

way they manage their teams.

Develop Talent - understand the skills, experience, aspirations and potential of their employees and coach them on current

performance and future potential. They ensure employees are receiving the feedback and insight needed to grow, develop and

realize their purpose.

Empower Teams - connect the team to the organization by aligning goals, purpose, and organizational objectives, and holding

them to account. They provide the support needed to remove barriers and connect their team to the broader ecosystem.

The salary range for this position is: $205,615.00 - $266,090.00. Kite considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com . Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma .

For jobs in the United States:

Kite Pharma is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex , age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance.

For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.

NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT

PAY TRANSPARENCY NONDISCRIMINATION PROVISION

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Kite Pharma provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Kite Pharma Employees and Contractors:

Please apply via the Internal Career Opportunities portal in Workday.