Post-Doctoral Scientist - Obesity Research - Boston

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. Were looking for people who are determined to make life better for people around the world.

We serve an extraordinary purpose. For more than 140 years, we have worked diligently to discover medicines that make life better. These discoveries start in Lilly Research Laboratories, where our scientists work to create new medicines that will help solve our worlds greatest health challenges.

Postdoctoral scientists help us continue this pursuit. During your experience you will get:

• Top industry research experience.
• Mentoring by some of Lillys top scientists.
• Laboratory training and education to further your development.
• Collaboration and networking across dozens of postdoctoral scientists and other researchers.

We are seeking an ambitious post-doctoral scientist, with strong research and communication skills, to build a highly collaborative, successful drug discovery and development team in the Obesity research group in Boston. The successful candidate will use a strong cell culture background and complementary wet laboratory experience to play a critical role in supporting end-to-end discovery efforts and established pipeline projects with an emphasis on anti-obesity therapeutics. The candidate will be responsible for setting up critical capabilities in the laboratory setting and working with other scientists within and across departments to achieve project and department goals.

Responsibilities

• Plan and independently carry out in vitro and in vivo experiments to evaluate targets/pathways, proof of concept and mechanism of action in obesity/diabetes and its associated complications.
• Build out robust cellular models such as 3D engineered skeletal and/or cardiac muscle bundles, using human or mammalian, immortalized, primary or induced pluripotent stem cell lines.
• Perform molecular and biochemical assessments (including qPCR, ELISA, Western blot, etc) on in vitro and ex vivo samples in collaboration with colleagues in other departments.
• Function independently, work within a team-oriented lab environment, and work within cross-functional project teams.
• Requirement for accurate record keeping, independent data analysis, and reporting of data in written and oral formats. Will perform work in full compliance with Lilly Research Policies and complete all required training activities in the timeframe specified.
• Present novel methods and findings at conferences and publish in high quality peer-reviewed journals.

Basic Qualifications

• Ph.D. in cellular and molecular biology, physiology or biomedical sciences.
• Expertise in skeletal and cardiac biology and physiology
• Experience with human or mammalian cell culture

Additional Skills/Preferences

• Self-directed and highly motivated individual who wants to learn and develop new techniques while continually pursuing research and publication goals.
• Excellent communicator (oral and written) with presentation experience.
• A proven track record of significant contributions to research projects, substantiated by first or co-authorship on peer-reviewed scientific publications in high-quality journals.
• High learning agility for new scientific concepts and operational systems.
• A track record of productive collaborations in interdisciplinary team environments.
• Proven ability in developing cellular models.
• Experience working with preclinical models of heart failure in vivo models.
• Prior work with 3D organoids and/or co-culture system.

Additional Information

This position is not permanent. It is for a fixed duration of two years with the potential to extend to 3 years and for a maximum of up to 4 years. There will be an opportunity to apply for full-time positions after the dura

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Actual compensation will depend on a candidates education, experience, skills, and geographic location. The anticipated wage for this position is

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lillys compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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