- Immunology R&D organization is seeking a highly motivated contractor to join our Systems Immunology early discovery team.
- We are looking for a candidate who is passionate about learning and has excellent attention to detail, to support target identification and validation efforts within our Immunology R&D division.
- The ideal candidate will have academic or industry experience in molecular and cell biology, with a preference for expertise in single-cell technologies, including single-cell next-generation sequencing (NGS), flow cytometry, and human cell culture.
- A willingness to learn and develop new techniques, as well as engage in in-depth analyses using diverse approaches, is essential.
- This role involves collaboration with various teams across R&D and other departments.
- Conduct high-throughput functional experiments with immune cells in vitro and characterize outcomes at the single-cell level using various omics techniques.
- Perform scRNAseq library preparations manually or with automated liquid handlers (e.g., Biomek i7) as part of a team.
- Operate flow cytometry and sorting machines to characterize the single-cell proteome and isolate targeted cells.
- Utilize sequencers and other laboratory instruments for NGS library quality control (e.g., Tapestation).
- Accurately document project details, protocols, and experimental procedures in the Electronic Lab Notebook (ELN).
- Conduct experiments and optimize protocols independently post-training, collaborating with colleagues to deliver high-quality data promptly.
- Interpret findings and effectively communicate scientific data, concepts, and recommendations to internal audiences.
- Collaborate with computational biologists and data scientists to generate and interpret scOMICs datasets.
- Work in matrixed environment to support various departments, participate in alignment meetings, and facilitate cross-functional collaboration.
- BS/MS with 1-3+ years of experience or equivalent education (PhD overqualified)
- Strong background in basic molecular biology and cellular biology/or genomics with experience in molecular biology lab techniques such as flow cytometry and DNA/RNA extraction, as well as familiarity with PBMC isolation, handling and cell culture.
- Experience with flow cytometry.
- Experience with human cell culture and functional experiments.
- Familiarity with 10X Genomics platforms.
- Background in R and immunology is a plus but not required.
- scRNAseq
- Single-cell RNA sequencing
- NGS
- next-generation sequencing
- 10x genomics
- PBMCs
- immune cells
- cell culture
- flow cytometry
- t cells
- b cells
- automated liquid handling
Job ID: 485780474
Originally Posted on: 7/17/2025
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