Scientist IV, Medicinal Chemistry

Every Exelixis employee is united in an ambitious cause: to launch innovative medicines that give patients, and their families hope for the future. In this pursuit, we know our employees are our most valuable asset. After operating in the challenging biotech sector for 25 years, we have a proven track record of resiliency in the face of adversity. The success of our lead product has provided a solid commercial foundation allowing us to reinvigorate our research efforts and grow our team in areas such as Drug Discovery, Clinical Development and Commercial.

As we expand our global partnerships and further reinvest in R&D to help us discover the next breakthrough for difficult-to-treat cancers, were seeking to add talented, dedicated employees to power our mission.

Cancer is our cause. Make it yours, too.

SUMMARY: Seeking a highly skilled and motivated synthetic chemist to join our small molecule drug discovery team. The ideal candidate will be an exceptional chemist who operates independently in the lab, designs synthetic routes, and successfully prepares novel compounds that drive projects forward while building strong working relationships with colleagues throughout the organization.

ESSENTIAL DUTIES AND RESPONSIBILITIES:

• Independently plans, optimizes, and executes syntheses of small molecules in accordance with project needs.

• Contributes creative solutions to synthetic problems, demonstrating independent thinking.

• Purifies, analyzes, and registers small molecules in the internal compound registration system.

• Presents progress in chemistry meetings and project teams meetings.

• As part of the lab chemistry team, is responsible for one or more group roles related to equipment, compound registration, compound inventory, lab safety and/or lab supplies.

• Demonstrates and fosters teamwork within Chemistry and with other cross-functional colleagues.

• Maintains lab notebooks in accordance with company policy and practice.

• Maintains familiarity with current scientific literature relevant to the research experiments or program.

• Complies with safe laboratory practices and EH&S guidelines.

• Contributes to the writing of technical documents, patents, scientific manuscripts, etc.

SUPERVISORY RESPONSIBILITIES:

• No supervisory responsibilities

EDUCATION & EXPERIENCE:

Education:

• Masters degree in a related discipline and a minimum of 3 years of related experience; or,

• Bachelors degree in a related discipline and a minimum of 5 years of related experience; or,

• Equivalent combination of education and industry medicinal chemistry experience.

Experience:

• Demonstrated independent thought and creativity leading to a solution of synthetic chemistry problems.

• Extensive experience in the design and execution of multi-step organic syntheses.

• Experience collaborating with colleagues in chemistry and related disciplines.

• Experience with modern methods of compound isolation, purification, and characterization.

SKILLS & ABILITIES:

• Ability to deliver high-quality work under tight timelines

• Excellent problem-solving and SAR analysis skills

• Excellent written and verbal communication skills

• Good people skills, flexibility, and ability to work well in a team environment

• Proficient in the use of modern analytical and purification approaches

• Skilled in the effective use of scientific literature and chemical/scientific databases

• Strong synthetic organic bench skills

JOB COMPLEXITY:

• Works effectively in a fast-paced team environment that is growing and evolving, requiring regular prioritization of projects to achieve pipeline deliverables.

• Exercises independent judgment in designing and executing syntheses to deliver results, including troubleshooting and optimizing challenging chemistry

#LI-HG1

If you like wild growth and working with happy, enthusiastic over-achievers, you'll enjoy your career with us!

Our compensation reflects the cost of labor across severalU.S. geographic markets, and we pay differently based on those defined markets. The base pay range for this positionis $100,000 - $141,500 annually. The base pay range may take into account the candidates geographic region, which will adjust the pay depending on the specific work location. The base pay offered will take into account the candidates geographic region, job-related knowledge, skills, experience and internal equity, among other factors.In addition to the base salary, as part of our Total Rewards program, Exelixis offers comprehensive employee benefits package, including a 401k plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Employees are also eligible for a discretionary annual bonus program, or if field sales staff, a sales-based incentive plan. Exelixis also offers employees the opportunity to purchase company stock, and receive long-term incentives, 15 accrued vacation days in their first year, 17 paid holidays including a company-wide winter shutdown in December, and up to 10 sick days throughout the calendar year.

DISCLAIMER
The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.

We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.