Research Scientist

Title: Research Scientist
Duration: 12+ Months
Work Location: Cambridge MA
Pay Range: $52/hr - $54/hr
Work Arrangement: 100% Onsite
Work Schedule: Monday to Friday, typical work hours are 9:00 AM to 5:00 PM
Parking Fee: Candidates must be agreeable with the client /day parking fee at Cambridge Crossings.

Applicants must be able to work directly for Artech on W2.

Top 3 to 5 Skills:

• Cell Culture
• Drug Combination Screen
• Molecular Biology

Position Summary

We are seeking an experienced individual with oncology discovery and/or translational expertise to join the Translational Research team within the Oncology Thematic Research Center at client in Cambridge, MA.
The qualified candidate will work broadly with the research organization to support drug discovery programs, by conducting experimental work in a translational setting, including developing and implementing cutting-edge technology and Client cellular, molecular and biochemical assays in cancer research and deliver data for Oncology TRC programs.

Detailed Position Responsibilities:
In the role as an Associate Scientist or Scientist within Oncology Translational Research, the ideal candidate will:

• Design, optimize, and set up high-throughput screening cellular assays to characterize drug responses and combinations in various in vitro oncology models.
• Conduct molecular, biochemical and related assays including qPCR, ELISA, Western blot, immunostaining and basic microscopy.
• Develop biomarker, pharmacodynamic and target engagement assays.
• Execute, troubleshoot and interpret scientific experiments with some supervision.
• Effectively communicate and document experimental procedures, analyze results and data through study reports and internal meetings.
• Collaborate with other team members in areas of responsibility.

Basic Qualifications:

• Bachelor’s Degree with 3–5 years of academic and/or industry experience
• Master’s Degree with 1–3 years of academic and/or industry experience
• PHD Over qualified
• BS or MS with at least 3–5 years of industry experience in cellular biology, oncology and molecular biology in the pharma or biotech setting may be considered.
• Hands-on experience in conducting cancer cell line and primary cell culture, expansion and functional assays.
• Experienced in the design and development of cell-based and molecular assays in a high-throughput manner.
• Experience performing analysis of protein and DNA/RNA samples using a variety of methodologies including but not limited to western blot, flow cytometry, qPCR, MSD/ELISA, RNAi, CRISPR.
• Proficiency in utilizing software such as Graph Pad, Client office etc. for data analysis and figure generation is required.
• Excellent organizational skills and ability to maintain accurate, detailed record-keeping of laboratory data.
• Ability to summarize and interpret scientific data and communicate well with peers and supervisors.

About the Team:
The Oncology Thematic Research Center at Client is a key research and early development engine, responsible for the discovery and development of Client oncology therapeutics for patients. Centered at our state-of-the-art research sites in Cambridge and Seattle, scientists focus on Client targets and pathways for tumors that are refractory to current therapies.

With a deep understanding of the causal human biology, we are able to leverage our multiple modality platforms to best match the modality to the mechanism and desired outcome. We are a fully integrated drug discovery through translational and early clinical development organization which exploits state-of-the-art in vitro, in vivo and ex-vivo models of Cancer biology and Immuno-oncology to identify and validate targets. We partner closely with colleagues in Translational Medicine, Informatics and Predictive Sciences and Early Clinical Development to generate biomarker and patient enrichment hypotheses to enable efficient decision making in early clinical trials.

We are optimally positioned to complement the world-class translational expertise, biology and leading academic research centers in the area. Our client research site in Cambridge Crossing will help us continue to deliver on our mission, positioning the company and our scientists in the heart of a vibrant ecosystem of world-class science, innovation, and business opportunities.