Principal Research Associate, Analytical Development

The Role

In this role, you will critical role in the development, optimization, and execution of robust cell-based bioassays to support the release and stability testing of mRNA-based therapeutics and vaccines. The ideal candidate will thrive in a collaborative, fast-paced environment and bring deep scientific rigor, independent problem-solving, and strong interpersonal skills. This role will partner closely with cross-functional stakeholders in Analytical Development, Quality, Process Development, and Research.

Heres What Youll Do

• Design, develop, and execute cell-based potency assays that assess the functional activity of Moderna's mRNA-based products

• Perform assay pre-qualification aligned with regulatory expectations for clinical and commercial programs

• Analyze and interpret complex data sets

• Troubleshoot assay performance, investigate deviations, and drive resolution in a timely and collaborative manner

• Serve as Subject Matter Expert (SME) for cell-based assay methodologies, providing technical support across internal and external project teams

• Author and review technical documents, including protocols, reports, and method transfer packages

• Evaluate emerging assay technologies and platforms for potential implementation

• Additional duties as may be assigned from time to time.

Heres What Youll Need ( Basic Qualifications)

• BS degree with 5 years of relevant industry experience, or MS degree with 2 years of experience in Biochemistry, Molecular Biology, Cell Biology, Immunology, or a related field

Heres What Youll Bring to the Table (Preferred Qualifications)

• Hands-on experience with mammalian cell culture and developing/executing cell-based potency assays

• Expertise with techniques such as flow cytometry, ELISA, luminescence/fluorescence-based reporter assays, HPLC, or mass spectrometry

• Strong analytical mindset with the ability to critically interpret results and guide assay optimization

• Demonstrated ability to manage multiple projects with shifting priorities in a dynamic environment

• Excellent organizational and communication skills, both written and verbal

• Self-motivated, team-oriented, and capable of working with minimal supervision

• A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative.

At Moderna, we believe that when you feel your best, you can do your best work. Thats why our US benefits and global well-being resources are designed to support youat work, at home, and everywhere in between.

• Best-in-class healthcare coverage, plus a suite of voluntary benefit programs to support your unique needs
• A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
• Lifestyle Spending Accounts to personalize your well-being journey
• Family planning and adoption benefits
• Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
• Savings and investment opportunities
• Location-specific perks and extras

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

Our Working Model

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.

Moderna is a smoke-free, alcohol-free, and drug-free work environment.

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Accommodations

Were focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at leavesandaccommodations@modernatx.com .

Export Control Notice

This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicants ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license.

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