Research Associate, Cell Culture Specialist

The purpose of a Research Associate, Cell Culture Specialist is to ensure proper growth of multiple cell lines in large quantities as well as optimizing the cells for screening studies.

Responsibilities:

• Manage mammalian tissue culture on immortalized and primary cell lines as well as neuro progenitor cells (NPCs)
• Manage thawing and expansion of cells for large scale high-throughput screening studies
• Maintain a wide variety of suspended and adherent cell lines at once
• Perform cell line optimization for screening studies for both manual and automated workflows and report findings to the manager
• Manage in all areas in support of cell culture and related duties as required including stocking, tracking inventory, material movement, filling out log sheets, and other special projects
• Perform calculations necessary for determining cell doubling time, cell concentration, seeding density, molarity, etc
• Assist in writing, revising, and improving project records, cell culture records and logs, SOPs, training materials, protocols, reports, and other required documentation
• Troubleshoot technical process, cell culture issues, and equipment problems
• Work in a dynamic, team-based environment
• Collaborate with other departments such as assay development, therapeutic area programs, production and QC as necessary
• Ability to work independently and in and across teams consisting of members with different degrees of knowledge or ability

Requirements:

• Master's degree in Biology, Biochemistry or related area with at least 5+ years relevant experience in cell culture
• Experience with maintaining a variety of adherent and suspended cell lines.
• Experience with neuro cell culture is a plus
• Able to identify and troubleshoot issues with cell cultures, for example, signs of over trypsinization, under- or over seeding, contamination from bacteria, fungus, or even other cell lines, senescence
• Experience with large scale cell culture is a huge plus
• Comfortable with calculations necessary for determining cell doubling time, cell concentration, seeding density, molarity, etc
• Effective multi-tasking and time management skills.
• Enjoys organizing individuals and projects
• Highly motivated, comfortable working in a results-oriented, fast paced, dynamic work environment
• Good oral and written communication skills
• Experience in data analysis and reporting
• Experience in large automation system and/or robotics is a plus

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