Postdoctoral Medicinal Chemist

RTI International (RTI) is both a global research institute and a leading international development organization based out of North Carolina. At RTI, you will find work you believe in, tackling some of the most complex global challenges of our time. Our mission is to impact the wellbeing of 1 billion people by 2030 through science-based solutions in climate, education, health, and equity. Our staff promote meaningful change around the world helping people live healthier, more productive, and more independent lives.

If you are looking for an opportunity to make a real difference, RTI is the place for you. Join us in our commitment to teamwork, belonging, and the passion to change the world.

The medicinal chemistry team within the Center for Drug Discovery supports client needs by conducting hit-to-lead and lead optimization. We integrate medicinal chemistry into larger projects focused on drug discovery and development, including computational chemistry, in vitro assay development and HTS screening, in vivo behavioral pharmacology, ADME/PK bioanalytics, and regulatory support.

We have an immediate need for a Medicinal Chemist to join our dynamic and rapidly expanding team. We are on the lookout for a highly motivated and organized individual who is eager to dive into the synthesis of monomers, building blocks, peptides, and oligonucleotides. In this exciting role, the candidate will design and develop innovative ligands to address a range of biological challenges, including kinases, G protein-coupled receptors, ion channels, and antimicrobial targets.

At RTI, you will be provided the opportunity to conduct meaningful work in a collaborative, cross-functional environment. We are focused on your career development and provide a generous benefits package that includes tuition reimbursement, parental leave, paid time off, medical/dental, and 401K.

This position is a two-year term assignment with potential for annual renewal.

In this role, the candidate will support experimental design and carry out compound synthesis independently or collaboratively. Responsibilities include ensuring accurate execution of studies, maintaining thorough records, analyzing data, and contributing to manuscript preparation for publication. The individual will also assist with grant applications, laboratory operations, and the training of junior staff. Additional duties include presenting research at conferences, reviewing scientific literature and patents, and other tasks as assigned by the principal investigator.

• Ph.D. in synthetic peptide chemistry or a related discipline field of study
• Proven expertise in solid-phase peptide and oligonucleotide synthesis.
• Well-demonstrated and extensive experience with a variety of chemical reactions.
• Proficiency in utilizing RP-HPLC, LC/MS, NMR, and chiral separation techniques.
• It is highly desirable to understand cell cultures and/or biological assays.
• Desirable to possess knowledge of basic computational techniques.
• Adept at working independently in a fast-paced environment.
• Proficient in English.

RTI is committed to Lead Forward. We innovate, develop talent, collaborate, communicate, think globally, act strategically, and engage inclusively. If that aligns with your values, we would like to hear from you. Join us and experience the RTI Difference.

For San Francisco, CA USA Job Postings Only: Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records. Further information is available here.

RTI accepts applications to our job openings from candidates with criminal histories or conviction records in accordance with all applicable laws, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.

For Applicants in Massachusetts Only: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

The anticipated pay range for this role is listed below. Our pay ranges represent national averages and may vary by location as a geographic differential may be applied to some locations within the United States. RTI considers multiple factors when making an offer including, for example: established salary range, internal budget, business needs, and education and years of work experience possessed by the applicant. Further, salary is merely one element to our offer.

At RTI, we demonstrate our commitment to rewarding individual and team achievement through a total rewards package. This package includes (among other things) a competitive base salary, a generous paid time off policy, merit based annual increases, bonus opportunities and a robust recognition program. Other benefits include a competitive range of insurance plans (including health, dental, life, and short-term and long-term disability), access to a retirement savings program such as a 401(k) plan, paid parental leave for all parents, financial assistance with adoption expenses or infertility treatments, financial reimbursement for education and developmental opportunities, an employee assistance program, and numerous other offerings to support a healthy work-life balance.